In a study using a first-of-its kind mouse model of aging that mimics breast cancer development in estrogen receptor-positive post-menopausal women, investigators at Georgetown Lombardi Comprehensive Cancer Center and colleagues ...
Dec 1, 2022
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About one third of patients with diabetes mellitus (DM) develop diabetic retinopathy (DR), a leading cause of blindness in working-age individuals. DR typically develops after many years of DM, and some patients do not develop ...
Nov 29, 2022
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Colonic motility disorders, especially problems associated with constipation and diarrhea, are common in adults and children, greatly impacting quality of life. A new study in The American Journal of Pathology identifies ...
Oct 11, 2022
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Using skin biopsy samples, investigators found that patients with severe COVID-19 had clots in small venous and arterial blood vessels in skin that appears normal. This was not seen in the skin of patents with other types ...
Jul 14, 2022
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Opioids are the gold standard for treatment of chronic and acute pain; however, their use may result in significant gastrointestinal side effects, including nausea, vomiting, and constipation. The reasons behind these side ...
Jul 6, 2022
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For military personnel who were deployed to Iraq and Afghanistan in the early 2000s, burn pits—areas where various waste was burned in open pits—were a visceral reminder of that hellish experience.
Jun 15, 2022
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The most common form of liver disease, alcohol-associated liver disease (ALD), contributes to half a million cirrhosis deaths worldwide annually. Odds of survival are very low and treatment options are limited. Two manifestations ...
Jun 14, 2022
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Using an artificial intelligence (AI) tool that emulates how humans visualize and is trained to recognize and classify images, investigators constructed a model that predicts the postoperative recurrence of Crohn disease ...
May 10, 2022
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Primary sclerosing cholangitis (PSC) is a disease in which inflammation causes scars in the bile duct, leading to liver failure, infections, and tumors. Up to 80% of PSC patients have inflammatory bowel disease. Major aspects ...
Mar 17, 2022
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Investigators studying lung cells have discovered that the normal repair process that occurs after lung disease or injury appears to be incomplete but still ongoing in patients who died of COVID-19 and non-COVID acute respiratory ...
Feb 16, 2022
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