American Journal of Pathology

Adult stem cells change their epigenome to generate new organs

A study developed by researchers at the IDIBELL, led by Manel Esteller, has identified epigenetic changes that occur in adult stem cells to generate different tissues of the human body.

Medical research created Oct 02, 2012 | popularity 5 / 5 (2) | comments 1

'Mad cow disease' in cattle can spread widely in ANS before detectable in CNS

Bovine spongiform encephalopathy (BSE, or "mad cow disease") is a fatal disease in cattle that causes portions of the brain to turn sponge-like. This transmissible disease is caused by the propagation of a misfolded form ...

Diseases, Conditions, Syndromes created Jul 09, 2012 | popularity 5 / 5 (1) | comments 0

Butter flavoring in microwave popcorn, thought safe for food industry workers, is respiratory hazard

The ingredient 2,3-pentanedione (PD), used to impart the flavor and aroma of butter in microwave popcorn, is a respiratory hazard that can also alter gene expression in the brain of rats. Manufacturers started using PD when ...

Health created Aug 13, 2012 | popularity 5 / 5 (1) | comments 0

Activation of cortical type 2 cannabinoid receptors ameliorates ischemic brain injury

A new study published in the March issue of The American Journal of Pathology suggests that cortical type 2 cannabinoid (CB2) receptors might serve as potential therapeutic targets for cerebral ischemia.

Medical research created Feb 21, 2013 | popularity 5 / 5 (1) | comments 0

Ranibizumab may prevent retinal detachment side effect

Proliferative vitreoretinopathy (PVR), or the formation of scar tissue in the eye, is a serious, sight-threatening complication in people recovering from surgical repair of retinal detachment. PVR is difficult to predict, ...

Ophthalmology created Apr 09, 2013 | popularity 5 / 5 (1) | comments 0

Researchers review muscular dystrophy therapies

Leading muscular dystrophy researcher Dean Burkin, of the University of Nevada School of Medicine summarizes the impact of a new protein therapeutic, MG53, for the treatment of Duchenne muscular dystrophy ...

Medical research created Jun 22, 2012 | popularity 4 / 5 (1) | comments 0 | with audio podcast

New hope for spinal cord injury patients

A new antibody could reverse the damage caused by trauma to the central nervous system, according to new research.

Diseases, Conditions, Syndromes created Aug 29, 2012 | popularity 3 / 5 (1) | comments 0

Tamoxifen ameliorates symptoms of Duchenne muscular dystrophy

A new study has found that tamoxifen, a well-known breast cancer drug, can counteract some pathologic features in a mouse model of Duchenne muscular dystrophy (DMD). At present, no treatment is known to produce ...

Diseases, Conditions, Syndromes created Jan 15, 2013 | popularity 3 / 5 (1) | comments 0 | with audio podcast