Annals of Neurology

Neuroscience

'Missing mutation' found in severe infant epilepsy

Researchers have discovered a "missing mutation" in severe infant epilepsy—long-suspected genetic changes that might trigger overactive, brain-damaging electrical signaling leading to seizures They also found early indications ...

Neuroscience

New insights on the neurobiology of dying

A new Annals of Neurology study provides insight into the neurobiology of dying. For the study, investigators performed continuous patient monitoring following Do Not Resuscitate - Comfort Care orders in patients with devastating ...

Parkinson's & Movement disorders

New brainstem changes identified in Parkinson's disease

A pioneering study has found that patients with Parkinson's disease have more errors in the mitochondrial DNA within the brainstem, leading to increased cell death in that area.

Alzheimer's disease & dementia

Lack of sleep boosts levels of Alzheimer's proteins

Have you resolved to take better care of yourself in the new year? Here's a relatively painless way to do it: Catch a few more zzz's every night. A third of American adults don't get enough sleep, according to the Centers ...

Neuroscience

Deep brain stimulation for the treatment of movement disorders

For the first time, researchers from Charité have shown that in patients with a type of movement disorder known as dystonia, a particular pattern of brain activity is linked to both the severity of symptoms and the clinical ...

Neuroscience

Tics are common in famous boys choir

'Tis the season for choirs to raise their voices in holiday song. A new Annals of Neurology study shows that there is a high frequency of tics in an extremely highly achieving group of pre-pubertal singers. 35% of 40 young ...

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