Hepatitis B is notoriously difficult to eradicate with currently available agents.. Now, in a new study, a novel form of "pegylated" interferon-β has reduced hepatitis B virus (HBV) infections in experimental human-derived ...
Apr 3, 2017
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New research is paving the way for the development of innovative drugs that restore antibiotic susceptibility in antibiotic-resistant superbugs such as Klebsiella pneumoniae, a main cause of fatal lung and bloodstream infections ...
Mar 13, 2017
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Researchers have known that part of the challenge in treating penicillin-resistant infections lies in understanding the way bacteria inactivate penicillin antibiotics. The enzymes that do this, beta-lactamases, chop up the ...
Mar 9, 2017
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Polymyxin antibiotics are used as a last resort to treat certain multidrug resistant bacteria. A team of investigators in China has discovered a new variant on a well-known gene that causes resistance to polymyxins and others. ...
Mar 6, 2017
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The deadly fungus, Candida auris, which has been found in hospitals, is resistant to entire classes of antimicrobial drugs, limiting treatment options for those infected. First reported in 2009, the fungus has been linked ...
Feb 24, 2017
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Combination therapy with two antibiotic compounds overcame pathogenic Enterobacteriaceae harboring a pernicious form of antibiotic resistance, in a bone-infected patient, where other drugs had failed. The research describing ...
Feb 6, 2017
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A new commentary from Patrick McNamara and Stuart Levy cautions that the Food and Drug Administration's ban on triclosan and 18 other biocidal chemicals that promote antibiotic resistance is only a starting point. Triclosan's ...
Dec 6, 2016
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Klebsiella pneumoniae bacteria exposed to chlorhexidine-containing disinfectants can become resistant to colistin, a last resort antibiotic often used against multidrug resistant pathogens. This is the first study to link ...
Oct 31, 2016
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Chikungunya virus has caused two recent massive outbreaks sickening millions of people. Now a team of researchers has shown that several existing compounds have potent activity against the critical CHIKV protease enzyme. ...
Oct 10, 2016
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August 8, 2016 - For the first time in Brazil, a particular antibiotic resistance mechanism conferring resistance to the important antibiotic, colistin, has been detected in a human. It was in a strain of Escherichia coli ...
Aug 8, 2016
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