Cancer Cell

Researchers discover master regulator that drives majority of lymphoma

A soon-to-be-tested class of drug inhibitors were predicted to help a limited number of patients with B-cell lymphomas with mutations affecting the EZH2 protein. However, a research team, led by investigators at Weill Cornell ...

Cancer created May 13, 2013 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Possible treatment for serious blood cancer

A single antibody could be the key to treating multiple myeloma, or cancer of the blood, currently without cure or long-term treatment.

Cancer created May 06, 2013 | popularity 5 / 5 (1) | comments 0

Scientists discover key process that allows colon cancer to metastasize

A team of 17 researchers, led by scientists Eduard Batlle and Elena Sancho in the Colorectal Cancer Laboratory at the Institute for Research in Biomedicine (IRB Barcelona), have determined that the ability ...

Cancer created Nov 12, 2012 | popularity 5 / 5 (5) | comments 0 | with audio podcast

Scientists discover new target for personalized cancer therapy

A common cancer pathway causing tumor growth is now being targeted by a number of new cancer drugs and shows promising results. A team of researchers at Case Western Reserve University School of Medicine have developed a ...

Cancer created May 02, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

How some prostate tumors resist treatment—and how it might be fixed

Hormonal therapies can help control advanced prostate cancer for a time. However, for most men, at some point their prostate cancer eventually stops responding to further hormonal treatment. This stage of ...

Cancer created Mar 18, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Mitochondrial metabolic regulator SIRT4 guards against DNA damage

(Medical Xpress)—Healthy cells don't just happen. As they grow and divide, they need checks and balances to ensure they function properly while adapting to changing conditions around them.

Cancer created Apr 05, 2013 | popularity 5 / 5 (4) | comments 2 | with audio podcast

Team finds gene that promotes drug resistance in cancer

Scientists from the University of Iowa and Brigham Young University (BYU) have identified a gene that may be a target for overcoming drug resistance in cancer. The finding could not only improve prognostic and diagnostic ...

Cancer created Jan 14, 2013 | popularity 4.8 / 5 (4) | comments 0 | with audio podcast

BRAF inhibitor treatment causes melanoma cells to shift how they produce energy

A multi-institutional study has revealed that BRAF-positive metastatic malignant melanomas develop resistance to treatment with drugs targeting the BRAF/MEK growth pathway through a major change in metabolism. The findings, ...

Cancer created Mar 08, 2013 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Mice at risk of asthma, allergies can fight off skin cancer

A molecule involved in asthma and allergies has now been shown to make mice resistant to skin cancer, according to scientists at Washington University School of Medicine in St. Louis.

Cancer created Oct 15, 2012 | popularity 5 / 5 (2) | comments 1 | with audio podcast

Gene inactivation drives spread of melanoma: study

Why do some cancers spread rapidly to other organs and others don't metastasize? A team of UNC researchers led by Norman Sharpless, MD, have identified a key genetic switch that determines whether melanoma, a lethal skin ...

Cancer created Jun 11, 2012 | popularity 3 / 5 (4) | comments 0 | with audio podcast

Scientists discover new way to target cancer

Scientists have discovered a new way to target cancer through manipulating a master switch responsible for cancer cell growth.

Cancer created Dec 12, 2011 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Study sheds light on how pancreatic cancer begins

A diagnosis of pancreatic cancer is particularly devastating since the prognosis for recovery is usually poor, with the cancer most often not detected until late stages.

Cancer created Nov 29, 2012 | popularity 4.2 / 5 (5) | comments 0 | with audio podcast

New study reveals how tumor suppressor p53 shut down in metastatic melanoma

Cancer cells are a problem for the body because they multiply recklessly, refuse to die and blithely metastasize to set up shop in places where they don't belong. One protein that keeps healthy cells from behaving this way ...

Cancer created Apr 25, 2013 | popularity not rated yet | comments 0 | with audio podcast

Study helps resolve debate about how tumors spread

A team of scientists, led by researchers at the University of California, San Diego School of Medicine, has shown for the first time how cancer cells control the ON/OFF switch of a program used by developing ...

Cancer created Nov 29, 2012 | popularity 3 / 5 (2) | comments 0 | with audio podcast

Cancer-causing gene alone doesn't trigger pancreatic cancer, study finds

More than a cancer-causing gene is needed to trigger pancreatic cancer, a study led by Mayo Clinic has found. A second factor creates a "perfect storm" that allows tumors to form, the researchers say. The study, published ...

Cancer created Sep 10, 2012 | popularity not rated yet | comments 0 | with audio podcast