Cancer Cell

Common mutation is culprit in acute leukemia relapse

Harvard stem cell scientists have identified a mutation in human cases of acute lymphoblastic leukemia that likely drives relapse. The research, published in Cancer Cell, could translate into improved patien ...

Mar 06, 2014
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Notch1 and osteoblasts play role in bone cancer initiation

(Medical Xpress)—A new mouse model of osteogenic sarcoma, a potentially deadly form of bone cancer, shows that high levels of Notch1, a gene that helps determine cell fate, can drive osteoblasts (cells that normally lead ...

Sep 08, 2014
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New mouse model points to therapy for liver disease

Non-alcoholic fatty liver disease (NAFLD) is a common affliction, affecting almost 30 percent of Americans, with a significant number suffering from its most severe form, called non-alcoholic steatohepatitis or NASH, which ...

Aug 18, 2014
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Team finds new route for ovarian cancer spread

Circulating tumor cells spread ovarian cancer through the bloodstream, homing in on a sheath of abdominal fatty tissue where it can grow and metastasize to other organs, scientists at The University of Texas MD Anderson Cancer ...

Jul 14, 2014
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