New research has found the most common form of breast cancer presents differing metabolic signatures in the blood of African American women with estrogen receptor-positive breast cancer compared with non-Hispanic white women. ...
Sep 11, 2023
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A new editorial paper titled "Subpopulations of AIB1 isoform-expressing breast cancer cells enable invasion and metastasis" has been published in Oncotarget.
Sep 6, 2023
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Most cancer deaths are due to the metastatic spread and growth of tumor cells at distant sites. Identifying appropriate treatments for patients with metastatic disease is challenging because of limited biomarkers and detection ...
Aug 15, 2023
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Catastrophe occasionally apologizes for itself by coughing up a consolation prize. World War II gave us penicillin. So let's count our blessings.
Aug 3, 2023
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In a landmark study of 125 Australian children with high-risk cancer—whose tumor cells were grown in the lab and tested against a suite of potential therapies—Children's Cancer Institute researchers have found that they ...
Aug 2, 2023
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Scientists have identified a protein that plays a pivotal role in the action of several emerging cancer therapies. The researchers say the discovery will likely aid efforts to fine-tune the use of immunotherapies against ...
Jul 31, 2023
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For solid tumors to grow efficiently, they generally need the help of non-transformed, endogenous cells around them. Through the communication of these cells with one another, networks form in the tumor's environment that ...
Jul 6, 2023
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Mutations in the KRAS gene are the major driver of pancreatic cancer. The resulting protein controls multiple signaling pathways involved in cell growth and survival. In cancer, the gene is mutated to be permanently "on," ...
Jun 29, 2023
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The development of hepatocellular carcinoma, liver cancer, is known to involve the abnormal activation of a signaling pathway called Wnt; however, the underlying mechanisms have not been fully understood, until now.
Jun 28, 2023
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Loss of two key "protector" proteins initiates epigenetic changes that transform healthy lung cells into cancerous ones, according to new research from Van Andel Institute scientists.
Jun 22, 2023
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