Cell Metabolism

Insight into the dazzling impact of insulin in cells

Australian scientists have charted the path of insulin action in cells in precise detail like never before. This provides a comprehensive blueprint for understanding what goes wrong in diabetes.

Medical research created May 21, 2013 | popularity 4.6 / 5 (8) | comments 0 | with audio podcast

Discovery of new hormone opens doors to new type 2 diabetes treatments

Harvard School of Public Health (HSPH) researchers have discovered that a particular type of protein (hormone) found in fat cells helps regulate how glucose (blood sugar) is controlled and metabolized (used for energy) in ...

Diabetes created May 07, 2013 | popularity 4.6 / 5 (8) | comments 1 | with audio podcast

Type 1 diabetes and heart disease linked by inflammatory protein

Type 1 (insulin-dependent) diabetes appears to increase the risk of heart disease, the leading cause of death among people with high blood sugar, partly by stimulating the production of calprotectin, a protein that sparks ...

Inflammatory disorders created May 07, 2013 | popularity 4.5 / 5 (2) | comments 0 | with audio podcast

Uncleaned cells mean weak muscles

The protein complex mTORC1 promotes muscle growth. However, should this complex remain constantly active, it impairs the ability of the cells to self-clean, causing myopathy. Scientists working with Markus ...

Medical research created Apr 23, 2013 | popularity 5 / 5 (3) | comments 0

Molecular hub links obesity, heart disease to high blood pressure

(Medical Xpress)—Obesity, heart disease, and high blood pressure (hypertension) are all related, but understanding the molecular pathways that underlie cause and effect is complicated.

Medical research created Apr 11, 2013 | popularity 3.3 / 5 (3) | comments 1 | with audio podcast

Key link between obesity and type 2 diabetes discovered

(Medical Xpress)—New research published in the journal Cell Metabolism has identified a key mechanism in the immune system involved in the development of obesity-linked type 2 diabetes. The findings open u ...

Medical research created Apr 04, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

White blood cell enzyme contributes to inflammation and obesity

Many recent studies have suggested that obesity is associated with chronic inflammation in fat tissues. Researchers at Sanford-Burnham Medical Research Institute (Sanford-Burnham) have discovered that an ...

Inflammatory disorders created Apr 02, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Surprising findings in mitochondrial biology change long-standing ideas on the protein MTERF1

New findings in mitochondrial biology thoroughly change the idea scientists had for 20 years on the role and importance of the protein MTERF1. For the first time, Max Planck researcher Mügen Terzioglu and her colleagues ...

Medical research created Apr 02, 2013 | popularity 4 / 5 (1) | comments 0 | with audio podcast

Cholesterol-lowering eye drops could treat macular degeneration

A new study raises the intriguing possibility that drugs prescribed to lower cholesterol may be effective against macular degeneration, a blinding eye disease.

Medical research created Apr 02, 2013 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Cell metabolism: Muscle loss can be caused by mitochondrial degradation induced by protein Mul1

Muscle withering can occur as part of the progression of many diseases, including cancer and muscular dystrophy, as well as during the normal aging process. Cellular organelles known as mitochondria provide ...

Medical research created Mar 13, 2013 | popularity 5 / 5 (1) | comments 0

Obesity makes fat cells act like they're infected

(Medical Xpress)—The inflammation of fat tissue is part of a spiraling series of events that leads to the development of type 2 diabetes in some obese people. But researchers have not understood what triggers ...

Medical research created Mar 05, 2013 | popularity 5 / 5 (5) | comments 0 | with audio podcast

Discovery of human genetic mutation could lead to new treatments for type 1 diabetes

In type 1 diabetes, the immune system destroys insulin-producing cells in the pancreas, but the precise cause has not been clear. A study published by Cell Press on March 5th in Cell Metabolism reveals that a ...

Genetics created Mar 05, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

New discoveries linking gut bacteria with cholesterol metabolism give hope for the future

(Medical Xpress)—Researchers at the Sahlgrenska Academy, University of Gothenburg, Sweden, show that cholesterol metabolism is regulated by bacteria in the small intestine. These findings may be important for the development ...

Medical research created Feb 18, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Lack of iron regulating protein contributes to high blood pressure of the lungs

A protein known to regulate iron levels in the body has an unexpectedly important role in preventing a form of high blood pressure that affects the lungs, and in stabilizing the concentration of red cells ...

Medical research created Feb 14, 2013 | popularity not rated yet | comments 0 | with audio podcast

Brain circuit that makes it hard for obese people to lose weight

(Medical Xpress)—Imagine you are driving a car, and the harder you press on the accelerator, the harder an invisible foot presses on the brake. That's what happens when obese people diet – the less food they eat, the ...

Medical research created Feb 06, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast