Cell Metabolism

Insight into the dazzling impact of insulin in cells

Australian scientists have charted the path of insulin action in cells in precise detail like never before. This provides a comprehensive blueprint for understanding what goes wrong in diabetes.

Medical research created May 21, 2013 | popularity 4.6 / 5 (8) | comments 0 | with audio podcast

Scientists identify molecular process in fat cells that influences stress and longevity

As part of their ongoing research investigating the biology of aging, the greatest risk factor for type 2 diabetes and other serious diseases, scientists at Joslin Diabetes Center have identified a new factor—microRNA ...

Medical research created Sep 26, 2012 | popularity 5 / 5 (5) | comments 1 | with audio podcast

Treatment target for diabetes, Wolfram syndrome

Inflammation and cell stress play important roles in the death of insulin-secreting cells and are major factors in diabetes. Cell stress also plays a role in Wolfram syndrome, a rare, genetic disorder that ...

Inflammatory disorders created Aug 07, 2012 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Surprising culprit behind chemo resistance in rare cancer

Researchers at Washington University School of Medicine in St. Louis have shown how an aggressive form of multiple myeloma resists chemotherapy.

Cancer created Jul 02, 2012 | popularity 5 / 5 (3) | comments 0 | with audio podcast

When you eat matters: Study offers drug-free intervention to prevent obesity, diabetes

It turns out that when we eat may be as important as what we eat. Scientists at the Salk Institute for Biological Studies have found that regular eating times and extending the daily fasting period may override ...

Medical research created May 17, 2012 | popularity 4.8 / 5 (17) | comments 7 | with audio podcast

Defective cellular waste removal explains why Gaucher patients often develop Parkinson's disease

Gaucher disease causes debilitating and sometimes fatal neurodegeneration in early childhood. Recent studies have uncovered a link between the mutations responsible for Gaucher disease and an increased risk ...

Parkinson's & Movement disorders created May 23, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Discovery of new hormone opens doors to new type 2 diabetes treatments

Harvard School of Public Health (HSPH) researchers have discovered that a particular type of protein (hormone) found in fat cells helps regulate how glucose (blood sugar) is controlled and metabolized (used for energy) in ...

Diabetes created May 07, 2013 | popularity 4.6 / 5 (8) | comments 1 | with audio podcast

Type 1 diabetes and heart disease linked by inflammatory protein

Type 1 (insulin-dependent) diabetes appears to increase the risk of heart disease, the leading cause of death among people with high blood sugar, partly by stimulating the production of calprotectin, a protein that sparks ...

Inflammatory disorders created May 07, 2013 | popularity 4.5 / 5 (2) | comments 0 | with audio podcast

Molecular hub links obesity, heart disease to high blood pressure

(Medical Xpress)—Obesity, heart disease, and high blood pressure (hypertension) are all related, but understanding the molecular pathways that underlie cause and effect is complicated.

Medical research created Apr 11, 2013 | popularity 3.3 / 5 (3) | comments 1 | with audio podcast

Key link between obesity and type 2 diabetes discovered

(Medical Xpress)—New research published in the journal Cell Metabolism has identified a key mechanism in the immune system involved in the development of obesity-linked type 2 diabetes. The findings open u ...

Medical research created Apr 04, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

White blood cell enzyme contributes to inflammation and obesity

Many recent studies have suggested that obesity is associated with chronic inflammation in fat tissues. Researchers at Sanford-Burnham Medical Research Institute (Sanford-Burnham) have discovered that an ...

Inflammatory disorders created Apr 02, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Surprising findings in mitochondrial biology change long-standing ideas on the protein MTERF1

New findings in mitochondrial biology thoroughly change the idea scientists had for 20 years on the role and importance of the protein MTERF1. For the first time, Max Planck researcher Mügen Terzioglu and her colleagues ...

Medical research created Apr 02, 2013 | popularity 4 / 5 (1) | comments 0 | with audio podcast

Cholesterol-lowering eye drops could treat macular degeneration

A new study raises the intriguing possibility that drugs prescribed to lower cholesterol may be effective against macular degeneration, a blinding eye disease.

Medical research created Apr 02, 2013 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Obesity makes fat cells act like they're infected

(Medical Xpress)—The inflammation of fat tissue is part of a spiraling series of events that leads to the development of type 2 diabetes in some obese people. But researchers have not understood what triggers ...

Medical research created Mar 05, 2013 | popularity 5 / 5 (5) | comments 0 | with audio podcast

Discovery of human genetic mutation could lead to new treatments for type 1 diabetes

In type 1 diabetes, the immune system destroys insulin-producing cells in the pancreas, but the precise cause has not been clear. A study published by Cell Press on March 5th in Cell Metabolism reveals that a ...

Genetics created Mar 05, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast