Human brain organoids are remarkable platforms for modeling features of human brain development and diseases. Building on methods to generate organoids to model different brain regions such as the cortex and the midbrain, ...
May 10, 2021
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Exeter scientists have discovered a simple, efficient way to recreate the early structure of the human embryo from stem cells in the laboratory. The new approach unlocks news ways of studying human fertility and reproduction.
May 5, 2021
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Researchers from the UCLA School of Dentistry have discovered a key molecule that allows cancer stem cells to bypass the body's natural immune defenses, spurring the growth and spread of head and neck squamous cell cancers. ...
May 4, 2021
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This year, more than 60,000 adults in the United States will be diagnosed with pancreatic cancer and, statistically, as few as 10 percent will survive five years after diagnosis, according to the American Cancer Society. ...
Apr 28, 2021
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Despite the prevalence of Alzheimer's, there are still no treatments, in part because it has been challenging to study how the disease develops. Now, scientists at the Salk Institute have uncovered new insights into what ...
Apr 27, 2021
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A mechanistic understanding of brain development requires a systematic survey of neural progenitor cell types, their lineage specification and maturation of postmitotic neurons. Cumulative evidences based on single-cell transcriptomic ...
Apr 21, 2021
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Metaplasia is defined as the replacement of a fully differentiated cell type by another. There are several classical examples of metaplasia, one of the most frequent is called Barrett's esophagus. Barrett's esophagus is characterized ...
Apr 21, 2021
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Researchers from the group of Hans Clevers (Hubrecht Institute) developed the first patient-derived organoid model for cervical cancer. They also modeled the healthy human cervix using organoids. In close collaboration with ...
Apr 13, 2021
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In a new study published in Cell Stem Cell, a team led by USC Stem Cell scientist Michael Bonaguidi, Ph.D., demonstrates that neural stem cells—the stem cells of the nervous system—age rapidly.
Apr 12, 2021
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Institute of Molecular Biotechnology of the Austrian Academy of Sciences have demonstrated that different viruses can lead to brain malformations through diverse mechanisms by using human brain organoid models. The results ...
Apr 9, 2021
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