Infections and other diseases can cause red blood cells to rupture, releasing the oxygen-binding molecule hemoglobin, which breaks down into heme. Free heme can cause significant inflammation and organ damage, leading to ...
Jun 1, 2023
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While the importance of the triggering receptor expressed on myeloid cells 2 (TREM2) is known in brain microglial function during neurodegenerative diseases, the function of the TREM2 cell receptor/protein is unknown in glioblastoma ...
A team of medical researchers affiliated with multiple institutions in the U.S. and the Netherlands has found a connection between the immune system and the brain in mice that could explain why psychological stress can lead ...
New research has identified a potential method for treating fragile X syndrome, a leading cause of autism spectrum disorders that is characterized by an inherited repeat of certain nucleotides within the DNA sequence of the ...
May 19, 2023
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Because serotonin is one of the primary chemicals the brain uses to influence mood and behavior, it is also the most common target of psychiatric drugs. To improve those drugs and to invent better ones, scientists need to ...
May 15, 2023
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Phenotypic sex differences are common in many aspects of health and disease. Despite the success of genome-wide association studies in improving the understanding of how genetic variation contributes to the manifestation ...
May 12, 2023
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By studying the unusual ability of bats to host viruses without significant illness, scientists at Duke-NUS Medical School have discovered a protein that could unlock new strategies for fighting inflammatory diseases in humans.
May 11, 2023
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Situated at the intersection of the human immune system and the brain are microglia, specialized brain immune cells that play a crucial role in development and disease. Although the importance of microglia is undisputed, ...
May 11, 2023
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The first study of humans with a rare immunodeficiency reveals how the immune system protects the body against pathogens known to cause serious diseases, such as tuberculosis and COVID-19. The research involving McGill University, ...
May 8, 2023
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Much of the human genome is made of regulatory regions that control which genes are expressed at a given time within a cell. Those regulatory elements can be located near a target gene or up to 2 million base pairs away from ...
May 8, 2023
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