Clinical Cancer Research
Stat5 predicts outcomes for prostate cancer patients after radical prostatectomy
Men who had high levels of the activated Stat5 protein in their prostate cancer after a radical prostatectomy were more likely to have a recurrence or die from the disease compared to men who had little to no presence of ...
Cancer
Oct 16, 2012 |
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New animal models can revolutionize the study of cancer
Some animal models developed by researchers at the Institute of Biomedical Research of Bellvitge (IDIBELL) and the Catalan Institute of Oncology (ICO) has served to validate the effectiveness of a new drug ...
Cancer
Oct 09, 2012 |
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Model confirms active surveillance as viable option for men with low-risk prostate cancer
A new research model has estimated that the difference in prostate cancer mortality among men with low-risk disease who choose active surveillance versus those who choose immediate treatment with radical prostatectomy is ...
Cancer
Sep 24, 2012 |
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Denosumab reduces burden of giant-cell tumor of the bone
Treatment with denosumab, a drug targeted against a protein that helps promote bone destruction, decreased the number of tumor giant cells in patients with giant-cell tumor of the bone, and increased new bone formation, according ...
Cancer
Sep 21, 2012 |
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Study shows vitamin E may decrease cancer risk in Cowden syndrome patients
Cleveland Clinic researchers have discovered that vitamin E may prevent cancer in patients with an under-recognized genetic disorder.
Cancer
Sep 17, 2012 |
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Researchers validate molecular signature to predict radiation therapy benefit
Researchers at Moffitt Cancer Center, working with colleagues in Sweden, the Netherlands and Puerto Rico, have validated a radiosensitivity molecular signature that can lead to better radiation therapy decisions for treating ...
Cancer
Aug 16, 2012 |
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Denosumab superior to zoledronic acid for breast cancer patients with bone metastases
Treatment with denosumab resulted in a greater reduction in skeletal-related events in patients with breast cancer that spread to the bones compared with zoledronic acid, while also maintaining health-related quality of life, ...
Cancer
Aug 14, 2012 |
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Grapefruit juice lets patients take lower dose of cancer drug
A glass a day of grapefruit juice lets patients derive the same benefits from an anti-cancer drug as they would get from more than three times as much of the drug by itself, according to a new clinical trial. The combination ...
Cancer
Aug 07, 2012 |
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'Master switch' experimental drug could treat different cancers
(Medical Xpress) -- A unique multi-target experimental drug could treat a range of cancer types, according to research published in Clinical Cancer Research today. ...
Cancer
Jul 11, 2012 |
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Research shows new prognosis tool for deadly brain cancer
A diagnosis of glioblastoma multiforme (GBM) is generally a death sentence, but new research from the University of Wisconsin-Madison lab of Dr. John Kuo shows that at least one subtype is associated with a longer life expectancy. ...
Cancer
Jun 20, 2012 |
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Clinical trial design supports original accelerated approval of sunitinib for GIST
Patients benefitted from an important design element in the pivotal phase III clinical trial that led to Food and Drug Administration and worldwide regulatory approval of sunitinib for the treatment of gastrointestinal stromal ...
Cancer
Jun 01, 2012 |
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Researchers discover biomarkers for prostate cancer detection, recurrence
Alterations to the "on-off" switches of genes occur early in the development of prostate cancer and could be used as biomarkers to detect the disease months or even years earlier than current approaches, a Mayo Clinic study ...
Cancer
May 14, 2012 |
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Harmless human virus may be able to boost the effects of chemotherapy
A naturally-occurring harmless human virus may be able to boost the effects of two standard chemotherapy drugs in some cancer patients, according to early stage trial data published in Clinical Cancer Research.
Cancer
Apr 03, 2012 |
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Tortoise and the hare: New drug stops rushing cancer cells, slow and steady healthy cells unharmed
The American Cancer Society estimates that 44,000 new cases of pancreatic cancer will be diagnosed this year and that 37,000 people will die from the disease. These are not strong odds. A new drug, rigosertib, allows pancreatic ...
Cancer
Mar 02, 2012 |
4.5 / 5 (2) |
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New tumor suppressor gene identified
A recent study published in Clinical Cancer Research suggests that the protein hVps37A suppresses tumor growth in ovarian cancer. The work, which was funded by the Austrian Science Fund FWF, shows, for th ...
Cancer
Feb 13, 2012 |
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