Clinical Cancer Research

Oxygen levels in tumours affect response to treatment

(Medical Xpress)—The genetic make-up of a patient's tumour could be used to personalise their treatment, and help to decide whether they would benefit from receiving additional drugs as part of their radiotherapy programme, ...

Nov 07, 2013
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Double-pronged attack could treat common children's cancer

A dual-pronged strategy using two experimental cancer drugs together could successfully treat a childhood cancer by inhibiting tumour growth and blocking off the escape routes it uses to become resistant to treatment, finds ...

Nov 01, 2013
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A simple test may catch early pancreatic cancer

Reporting on a small preliminary study, Johns Hopkins researchers say a simple blood test based on detection of tiny epigenetic alterations may reveal the earliest signs of pancreatic cancer, a disease that is nearly always ...

Oct 23, 2013
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MicroRNA-31 might predict lung-cancer spread

(Medical Xpress)—Determining whether a patient's lung cancer has spread to nearby lymph nodes is critical for identifying the most effective therapy, but it usually requires surgery. A new study suggests, however, that ...

Sep 24, 2013
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New marker identified for early diagnosis of lung cancer

A protein called isocitrate dehydrogenase (IDH1) is present at high levels in lung cancers and can be detected in the blood, making it a noninvasive diagnostic marker for lung cancers, according to a study published in Clinical Ca ...

Sep 17, 2013
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Scientists identify targets for melanoma immunotherapy

Using a highly sensitive technology called NanoString, researchers have identified seven targets that could potentially be used to develop new immunotherapies for patients with metastatic melanoma, according to a study published ...

Sep 10, 2013
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New hope in the fight against childhood cancer

Cancer Research UK scientists at the University of Southampton are seeing positive results in a pre-clinical trial that could bring treatments for a particular aggressive form of childhood cancer closer to reality.

Jul 11, 2013
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New drug may help immune system fight cancer

(HealthDay)—An experimental drug that taps the power of the body's immune system to fight cancer is shrinking tumors in patients for whom other treatments have failed, an early study shows.

May 16, 2013
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