Clinical Cancer Research

New tumor suppressor gene identified

A recent study published in Clinical Cancer Research suggests that the protein hVps37A suppresses tumor growth in ovarian cancer. The work, which was funded by the Austrian Science Fund FWF, shows, for th ...

Cancer created Feb 13, 2012 | popularity 4.8 / 5 (4) | comments 0

Grapefruit juice lets patients take lower dose of cancer drug

A glass a day of grapefruit juice lets patients derive the same benefits from an anti-cancer drug as they would get from more than three times as much of the drug by itself, according to a new clinical trial. The combination ...

Cancer created Aug 07, 2012 | popularity 5 / 5 (3) | comments 0 | with audio podcast

New drug may help immune system fight cancer

(HealthDay)—An experimental drug that taps the power of the body's immune system to fight cancer is shrinking tumors in patients for whom other treatments have failed, an early study shows.

Cancer created May 16, 2013 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Researchers discover biomarkers for prostate cancer detection, recurrence

Alterations to the "on-off" switches of genes occur early in the development of prostate cancer and could be used as biomarkers to detect the disease months or even years earlier than current approaches, a Mayo Clinic study ...

Cancer created May 14, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Scientists create method to personalize chemotherapy drug selection

In laboratory studies, scientists at the Johns Hopkins Kimmel Cancer Center have developed a way to personalize chemotherapy drug selection for cancer patients by using cell lines created from their own tumors.

Cancer created Feb 14, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

New drug enhances radiation treatment for brain cancer in preclinical studies

A novel drug may help increase the effectiveness of radiation therapy for the most deadly form of brain cancer, report scientists at Virginia Commonwealth University Massey Cancer Center. In mouse models of human glioblastoma ...

Cancer created May 14, 2013 | popularity 5 / 5 (2) | comments 0

Tortoise and the hare: New drug stops rushing cancer cells, slow and steady healthy cells unharmed

The American Cancer Society estimates that 44,000 new cases of pancreatic cancer will be diagnosed this year and that 37,000 people will die from the disease. These are not strong odds. A new drug, rigosertib, allows pancreatic ...

Cancer created Mar 02, 2012 | popularity 4.5 / 5 (2) | comments 0

Harmless human virus may be able to boost the effects of chemotherapy

A naturally-occurring harmless human virus may be able to boost the effects of two standard chemotherapy drugs in some cancer patients, according to early stage trial data published in Clinical Cancer Research.

Cancer created Apr 03, 2012 | popularity 5 / 5 (1) | comments 0

'Master switch' experimental drug could treat different cancers

(Medical Xpress) -- A unique multi-target experimental drug could treat a range of cancer types, according to research published in Clinical Cancer Research today. ...

Cancer created Jul 11, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Optimal dose suggested for dasatinib in ovarian cancer

(HealthDay)—A phase I trial of dasatinib combined with paclitaxel and carboplatin has determined the optimal dose of dasatinib and suggested some efficacy in women with advanced or recurrent ovarian cancer, ...

Cancer created Nov 19, 2012 | popularity 5 / 5 (1) | comments 0

The HER2 paradox: HER2-positive stem cells found in HER2-negative breast cancer

A multicenter study led by researchers at UC Davis describes new, paradoxical characteristics of the most common type of breast cancer. The findings shed light on how the disease can evade treatment and could improve diagnosis ...

Cancer created Dec 14, 2012 | popularity 5 / 5 (1) | comments 0

Researchers identify genetic variation behind acute myeloid leukemia treatment success

Researchers from the College of Pharmacy and Medical School working within the Masonic Cancer Center, University of Minnesota, have partnered to identify genetic variations that may help signal which acute myeloid leukemia ...

Cancer created Feb 26, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

HPV improves survival for African-Americans with throat cancer

Even though the human papillomavirus (HPV) is a risk factor for certain head and neck cancers, its presence could make all the difference in terms of survival, especially for African Americans with throat cancer, according ...

Cancer created Mar 28, 2013 | popularity 5 / 5 (1) | comments 0

Agent shows ability to suppress brain metastasis and related damage

(Medical Xpress) -- Scientists are one step closer to repairing the damage caused by brain metastasis, a major challenge in cancer treatment, according to data published in Cancer Research, a journal of the American Associ ...

Cancer created Jan 03, 2012 | popularity 4 / 5 (1) | comments 0 | with audio podcast