Clinical Cancer Research
New drug may help immune system fight cancer
(HealthDay)—An experimental drug that taps the power of the body's immune system to fight cancer is shrinking tumors in patients for whom other treatments have failed, an early study shows.
Cancer
May 16, 2013 |
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Researchers identify genetic variation behind acute myeloid leukemia treatment success
Researchers from the College of Pharmacy and Medical School working within the Masonic Cancer Center, University of Minnesota, have partnered to identify genetic variations that may help signal which acute myeloid leukemia ...
Cancer
Feb 26, 2013 |
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Scientists create method to personalize chemotherapy drug selection
In laboratory studies, scientists at the Johns Hopkins Kimmel Cancer Center have developed a way to personalize chemotherapy drug selection for cancer patients by using cell lines created from their own tumors.
Cancer
Feb 14, 2013 |
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Nanotech'ed RNA drug reduces ovarian cancer tumors by 83 percent
By loading fragile RNA into silicon nanoparticles, researchers from The Methodist Hospital and two other institutions found a new drug delivery system can reduce the size of ovarian tumors by as much as 83 ...
Cancer
Feb 14, 2013 |
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Vital children's cancer drug being underdosed
(Medical Xpress)—A study has found that many patients receiving a potentially life-saving drug for the childhood cancer neuroblastoma are potentially being under-dosed. Every year in the UK approximately 100 children aged ...
Cancer
Jan 18, 2013 |
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Ability to metabolize tamoxifen affects breast cancer outcomes, study confirms
For nearly a decade, breast cancer researchers studying the hormone therapy tamoxifen have been divided as to whether genetic differences in a liver enzyme affect the drug's effectiveness and the likelihood breast cancer ...
Cancer
Dec 27, 2012 |
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Model confirms active surveillance as viable option for men with low-risk prostate cancer
A new research model has estimated that the difference in prostate cancer mortality among men with low-risk disease who choose active surveillance versus those who choose immediate treatment with radical prostatectomy is ...
Cancer
Sep 24, 2012 |
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Denosumab superior to zoledronic acid for breast cancer patients with bone metastases
Treatment with denosumab resulted in a greater reduction in skeletal-related events in patients with breast cancer that spread to the bones compared with zoledronic acid, while also maintaining health-related quality of life, ...
Cancer
Aug 14, 2012 |
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Grapefruit juice lets patients take lower dose of cancer drug
A glass a day of grapefruit juice lets patients derive the same benefits from an anti-cancer drug as they would get from more than three times as much of the drug by itself, according to a new clinical trial. The combination ...
Cancer
Aug 07, 2012 |
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'Master switch' experimental drug could treat different cancers
(Medical Xpress) -- A unique multi-target experimental drug could treat a range of cancer types, according to research published in Clinical Cancer Research today. ...
Cancer
Jul 11, 2012 |
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Research shows new prognosis tool for deadly brain cancer
A diagnosis of glioblastoma multiforme (GBM) is generally a death sentence, but new research from the University of Wisconsin-Madison lab of Dr. John Kuo shows that at least one subtype is associated with a longer life expectancy. ...
Cancer
Jun 20, 2012 |
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Researchers discover biomarkers for prostate cancer detection, recurrence
Alterations to the "on-off" switches of genes occur early in the development of prostate cancer and could be used as biomarkers to detect the disease months or even years earlier than current approaches, a Mayo Clinic study ...
Cancer
May 14, 2012 |
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Agent shows ability to suppress brain metastasis and related damage
(Medical Xpress) -- Scientists are one step closer to repairing the damage caused by brain metastasis, a major challenge in cancer treatment, according to data published in Cancer Research, a journal of the American Associ ...
Cancer
Jan 03, 2012 |
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New drug enhances radiation treatment for brain cancer in preclinical studies
A novel drug may help increase the effectiveness of radiation therapy for the most deadly form of brain cancer, report scientists at Virginia Commonwealth University Massey Cancer Center. In mouse models of human glioblastoma ...
Cancer
May 14, 2013 |
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Study finds experimental drug inhibits growth in all stages of common kidney cancer
Researchers at Mayo Clinic's campus in Florida have discovered a protein that is overly active in every human sample of kidney cancer they examined. They also found that an experimental drug designed to block the protein's ...
Cancer
Apr 30, 2013 |
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