Developmental Cell

Giant proteins determine properties of neurons

Giant membrane-associated proteins called ankyrins extend into the cytoplasm to arrange and stabilize microtubules in axons and synapses. This determines not only the diameter and hence the functional properties ...

Apr 14, 2015
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Team identifies oncogene regulated by nutrients

Scientists from the Growth Factors, Nutrients and Cancer Group at the Spanish National Cancer Research Center (CNIO), led by Nabil Djouder, have discovered that the MCRS1 protein, in response to an excess of nutrients, induces ...

Apr 13, 2015
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Golgi trafficking controlled by G proteins

A family of proteins called G proteins are a recognized component of the communication system the human body uses to sense hormones and other chemicals in the bloodstream and to send messages to cells. In work that further ...

Apr 09, 2015
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Origin of cancer wasting identified in fruit flies

The progressive wasting of muscle and fat tissue throughout the body is one of the most visible and heartbreaking manifestations of cancer, yet little is known about how tumors cause distant tissues to degenerate. ...

Apr 06, 2015
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Promising drug target identified in medulloblastoma

Scientists at Dana-Farber/Boston Children's Cancer and Blood Disorders Center have identified a protein critical to both the normal development of the brain and, in many cases, the development of medulloblastoma, a fast-growing ...

Mar 26, 2015
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How to myelinate a nerve

(Medical Xpress)—Demyelinating diseases, like MS or ALS, attack an otherwise healthy nervous system and leave its owner a prisoner in their own body. The harder big pharma searches for—and fails to find—miracle ...

Mar 24, 2015
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