Developmental Cell
Study uncovers molecular role of gene linked to blood vessel formation
University of North Carolina researchers have discovered that disrupting a gene that acts as a regulatory switch to turn on other genes can keep blood vessels from forming and developing properly.
Medical research
Apr 29, 2013 |
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Growing new arteries, bypassing blocked ones
Scientific collaborators from Yale School of Medicine and University College London (UCL) have uncovered the molecular pathway by which new arteries may form after heart attacks, strokes and other acute illnesses bypassing ...
Medical research
Apr 29, 2013 |
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New insights into the development of the heart
Viewed from the outside, our body looks completely symmetrical. However, most internal organs – including the heart – are formed asymmetrically. The right side of the heart is responsible for pulmonary circulation; the ...
Medical research
Mar 26, 2013 |
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Researchers find that two antagonistic proteins help keep leukemia at bay, pointing to new potential treatments
Two proteins that scientists once thought carried out the same functions are actually antagonists of each other, and keeping them in balance is key to preventing diseases such as cancer, according to new findings published ...
Cancer
Feb 27, 2013 |
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Tweaking gene expression to repair lungs
A healthy lung has some capacity to regenerate itself like the liver. In COPD, these reparative mechanisms fail. HDAC therapies may be useful for COPD, as well as other airway diseases. The levels of HDAC2 ...
Medical research
Feb 25, 2013 |
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Not all fat is packaged the same way, researchers find
Fat is stored in the body in two distinct ways, Yale researchers have discovered. While the finding may not help people shed excess pounds, it may shed light on how to prevent health problems associated with ...
Overweight and Obesity
Feb 15, 2013 |
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Researchers find possible genetic clues to organ development, birth defects (w/ Video)
(Medical Xpress)—Using cutting-edge time-lapse photography, University of Southern California (USC) researchers have discovered clues to the development of the head at the cellular level, which could point scientists to ...
Medical research
Feb 11, 2013 |
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Novel microscale epigenomics technology: Possible to study the epigenome of rare cell populations and biopsy samples
Scientists at A*STAR's Genome Institute of Singapore (GIS) have successfully developed a method to map the epigenome using 100 times fewer cells than was previously possible. The discovery, published in the journal Developmental Ce ...
Genetics
Feb 11, 2013 |
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Plvap/PV1 critical to formation of the diaphragms in endothelial cells
Dartmouth scientists have demonstrated the importance of the gene Plvap and the structures it forms in mammalian physiology in a study published in December by the journal Developmental Cell.
Cancer
Jan 03, 2013 |
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Cell proliferation is a key factor in degenerative diseases and cancers
(Medical Xpress)—A newly-engineered strain of mice whose dividing cells express a fluorescent protein could open the door to new methods of regulating cell proliferation in humans. Cell proliferation plays ...
Medical research
Nov 28, 2012 |
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Cilia guide neuronal migration in developing brain
A new study demonstrates the dynamic role cilia play in guiding the migration of neurons in the embryonic brain. Cilia are tiny hair-like structures on the surfaces of cells, but here they are acting more ...
Medical research
Nov 12, 2012 |
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Using planarian flatworms to understand organ regeneration
Researchers report in the journal Developmental Cell that they have identified genes that control growth and regeneration of the intestine in the freshwater planarian Schmidtea mediterranea.
Medical research
Oct 25, 2012 |
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Cortex development depends on a protein
As outlined in a study published in Developmental Cell, researchers have discovered a novel function for p27 in the control of interneuron migration in the developing cerebral cortex.
Medical research
Oct 02, 2012 |
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Study adds to efforts to find more effective anti-inflammatory drugs
Researchers have discovered a previously unknown function for a protein that could add to the expanding arsenal of potential new drugs for battling inflammation and tissue fibrosis in a number of disease processes.
Inflammatory disorders
Sep 27, 2012 |
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Study uncovers mechanism by which tumor suppressor MIG6 triggers cell suicide
Death plays a big role in keeping things alive. Consider the tightly orchestrated suicide of cells—a phenomenon essential to everything from shaping an embryo to keeping it free of cancer later in life. ...
Cancer
Sep 24, 2012 |
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