Developmental Cell

Growing new arteries, bypassing blocked ones

Scientific collaborators from Yale School of Medicine and University College London (UCL) have uncovered the molecular pathway by which new arteries may form after heart attacks, strokes and other acute illnesses bypassing ...

Medical research created Apr 29, 2013 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Newly discovered protein makes sure brain development isn't 'botched'

(Medical Xpress) -- Johns Hopkins scientists have discovered a protein that appears to play an important regulatory role in deciding whether stem cells differentiate into the cells that make up the brain, as well as countless ...

Neuroscience created May 22, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Locating ground zero: How the brain's emergency workers find the disaster area

Like emergency workers rushing to a disaster scene, cells called microglia speed to places where the brain has been injured, to contain the damage by 'eating up' any cellular debris and dead or dying neurons. ...

Neuroscience created May 24, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Clues found to way embryonic kidney maintains its fleeting stem cells

Studying mice and humans, researchers at Washington University School of Medicine in St. Louis and their collaborators in Paris have identified two proteins that are required to maintain a supply of stem cells ...

Medical research created Jun 11, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Double drug combo could shut down abnormal blood vessel growth that feeds disease

A new study by researchers at Weill Cornell Medical College shows combining two already-FDA approved drugs may offer a new and potent punch against diseases in which blood vessel growth is abnormal—such as cancer, diabetic ...

Medical research created Sep 10, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Using planarian flatworms to understand organ regeneration

Researchers report in the journal Developmental Cell that they have identified genes that control growth and regeneration of the intestine in the freshwater planarian Schmidtea mediterranea.

Medical research created Oct 25, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Cilia guide neuronal migration in developing brain

A new study demonstrates the dynamic role cilia play in guiding the migration of neurons in the embryonic brain. Cilia are tiny hair-like structures on the surfaces of cells, but here they are acting more ...

Medical research created Nov 12, 2012 | popularity 5 / 5 (2) | comments 1 | with audio podcast

Not all fat is packaged the same way, researchers find

Fat is stored in the body in two distinct ways, Yale researchers have discovered. While the finding may not help people shed excess pounds, it may shed light on how to prevent health problems associated with ...

Overweight and Obesity created Feb 15, 2013 | popularity 4.5 / 5 (2) | comments 0 | with audio podcast

Researchers discover the cause of an inherited form of epilepsy

Researchers at McGill University have discovered the cause of an inherited form of epilepsy. The disease, known as double-cortex syndrome, primarily affects females and arises from mutations on a gene located on the X chromosome. ...

Medical research created Jun 21, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Scientists discover key pathway for development of insulin-producing cells

(Medical Xpress) -- Researchers at the Stanford University School of Medicine have identified a molecular signaling pathway that drives the growth and maturation of young human beta cells — the insulin-producing cell ...

Medical research created Jul 17, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Gene 'switch' may explain DiGeorge syndrome severity

The discovery of a 'switch' that modifies a gene known to be essential for normal heart development could explain variations in the severity of birth defects in children with DiGeorge syndrome.

Genetics created Aug 23, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Cortex development depends on a protein

As outlined in a study published in Developmental Cell, researchers have discovered a novel function for p27 in the control of interneuron migration in the developing cerebral cortex.

Medical research created Oct 02, 2012 | popularity 5 / 5 (1) | comments 0

Cell proliferation is a key factor in degenerative diseases and cancers

(Medical Xpress)—A newly-engineered strain of mice whose dividing cells express a fluorescent protein could open the door to new methods of regulating cell proliferation in humans. Cell proliferation plays ...

Medical research created Nov 28, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Novel microscale epigenomics technology: Possible to study the epigenome of rare cell populations and biopsy samples

Scientists at A*STAR's Genome Institute of Singapore (GIS) have successfully developed a method to map the epigenome using 100 times fewer cells than was previously possible. The discovery, published in the journal Developmental Ce ...

Genetics created Feb 11, 2013 | popularity 5 / 5 (1) | comments 0

Researchers find that two antagonistic proteins help keep leukemia at bay, pointing to new potential treatments

Two proteins that scientists once thought carried out the same functions are actually antagonists of each other, and keeping them in balance is key to preventing diseases such as cancer, according to new findings published ...

Cancer created Feb 27, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast