Developmental Cell

Oncology & Cancer

Study may explain why once-promising cancer drugs failed

Nearly two decades after a class of once-promising cancer drugs called MMP inhibitors mysteriously failed in clinical trials, scientists think they may have an explanation for what went wrong.

Neuroscience

Enzyme helps build motor that drives neuron death

A biochemistry instructor curious about an enzyme discovered in the damaged neurons of people with multiple sclerosis made a leap toward a potential cure for countless neurodegenerative ills.

Medical research

Researchers recreate the adrenal gland in a petri dish

Sitting atop the kidneys, the adrenal gland plays a pivotal role in maintaining a healthy body. Responding to signals from the brain, the gland secretes hormones that support critical functions like blood pressure, metabolism, ...

Oncology & Cancer

A barrier that keeps cancer at bay

Activins are proteins involved in a number of important biological functions, including the regulation of the menstrual cycle, cell proliferation, differentiation, apoptosis, metabolism, homeostasis, immune response, wound ...

Oncology & Cancer

Pancreatic cancer: Mutable cancer cells are more dangerous

Pancreatic cancer often spreads, forming metastases in the liver or lungs. The prognosis is better for patients with metastases in the lungs. However, the cancer cells' ability to alter their characteristics and shape influences ...

Genetics

Researchers unlock the secrets of liver regeneration

In a recent study published in the journal Developmental Cell, NYU Abu Dhabi researchers have reported a new way in which the liver is primed to regenerate itself. They found that by stripping parts of the epigenome, which ...

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