Diabetes

Diabetes

Short-chain fatty acids in diet stimulate fat utilization

(HealthDay)—Short-chain fatty acids (SCFAs), the main products of dietary fiber fermentation, induce a peroxisome proliferator-activated receptor (PPAR) γ-dependent switch from lipid synthesis to lipid utilization, according ...

Diabetes

Changes in adipose tissue with lack of insulin, IGF-1 receptors

(HealthDay)—Mice lacking either the insulin receptor (IR), insulin-like growth factor 1 receptor (IGF1R), or both have disruptions in white and brown adipose tissue (WAT and BAT) formation, with an almost complete absence ...

Diabetes

Radiation effect on epigenetic modifiers may up metabolic risk

(HealthDay)—Total body irradiation alters intracellular signaling and epigenetic pathways regulating cell proliferation and differentiation of skeletal muscle and adipose progenitor cells, according to an experimental study ...

Diabetes

Metformin influences nitrogen and urea metabolism

The most frequently prescribed oral antidiabetic drug metformin significantly affects metabolic pathways. This was reported by scientists from the Helmholtz Zentrum München together with colleagues from the German Diabetes ...

Diabetes

Mechanism behind age-dependent diabetes discovered

Ageing of insulin-secreting cells is coupled to a progressive decline in signal transduction and insulin release, according to a recent study by researchers at Karolinska Institutet in Sweden. The finding, which is published ...

Diabetes

Novel lipid mediators may play role in omega-3 PUFA effects

(HealthDay)—Novel lipid mediators may be involved in the beneficial effects associated with omega-3 polyunsaturated fatty acids (PUFAs) in obesity, according to a study published online June 16 in Diabetes.

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