EMBO Journal

Medical research

Mechanisms behind aggressive cancer metastases uncovered

Breast cancer spreading to other organs usually heralds a poorer prognosis. Researchers at the University and University Hospital of Basel have discovered a process that helps breast cancer cells implant themselves in certain ...

Genetics

Epigenetic profiling identifies potential COPD treatment targets

Impaired function of lung fibroblast is considered causative for symptoms of the incurable lung disease COPD (Chronic Obstructive Pulmonary Disease). Using high-resolution epigenetic profiling, German and British scientists ...

Diseases, Conditions, Syndromes

Study sheds light on a mitochondrial disease

Scientists at the University of Liverpool have figured out how mutations in a gene called FBXL4 can lead to an excess of mitophagy—the disposal of mitochondria, the 'power stations' within nearly all human cells.

Medical research

Newly discovered surface structures may affect immune function

Using new microscopic methods in combination with machine learning-based image analysis, researchers from Freiburg have discovered new structures on the surface of living B cells that affect the distribution and possibly ...

Medical research

Possible therapeutic approach to fight incurable blood cancer

Multiple myeloma (MM) is the second most common type of blood cancer. It attacks the plasma cells in the blood. A team at the Technical University of Munich (TUM) has now discovered a mechanism which provides indications ...

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