EMBO Molecular Medicine

Medical research

Preventing metastasis: An antibody with therapeutic potential

A receptor in the cell layer that lines the blood vessels from the inside stimulates both the formation of new blood vessels in tumors and metastasis. Scientists at the German Cancer Research Center in Heidelberg (DKFZ) and ...

Neuroscience

Alzheimer's risk genes converge on microglia

DNA determines a large part of the risk for Alzheimer's disease, but it remained unclear how many genetic risk factors contribute to disease. A team led by Prof. Bart De Strooper (VIB-KU Leuven) and Dr. Mark Fiers now show ...

Medical research

Tracking down 'illegal parkers' in cancer cells

Squamous cell carcinoma is a very unusual type of cancer. It occurs in many tissues—for example in the lungs, esophagus, pancreas, throat and pharynx, and on the skin. Due to the many mutations in this type of cancer, treatment ...

Alzheimer's disease & dementia

Mouse study suggests immune cells could protect against Alzheimer's

Scientists at the German Center for Neurodegenerative Diseases (DZNE), the Ludwig-Maximilians-Universitaet (LMU) Munich and Denali Therapeutics (South San Francisco, CA, U.S.) have developed an approach to stimulate immune ...

Oncology & Cancer

Cheap drug may alleviate treatment-resistance in leukemia

A common and inexpensive drug may be used to counteract treatment resistance in patients with acute myeloid leukemia (AML), one of the most common forms of blood cancer. This is the conclusion of a study in mice and human ...

Genetics

Genetic alterations in skin stem cells can trigger psoriasis

Psoriasis is not a congenital disorder—it only occurs later on in life and has various causes, such as stress or UV irradiation, some of which have not yet been explored. In biomedical science, this frequently occurring ...

Medical research

Biomarker for schizophrenia can be detected in human hair

Working with model mice, postmortem human brains, and people with schizophrenia, researchers at the RIKEN Center for Brain Science in Japan have discovered that a subtype of schizophrenia is related to abnormally high levels ...

Medical research

Exploring the effect of fasting on age-related diseases

There are many indications that fasting promotes longevity. In recent years, much attention has been devoted to so-called caloric restriction mimetics (CMRs), substances that simulate the health-promoting effects of fasting ...

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