EMBO Molecular Medicine
Study identifies new approach to improving treatment for MS and other conditions
(Medical Xpress)—Working with lab mice models of multiple sclerosis (MS), UC Davis scientists have detected a novel molecular target for the design of drugs that could be safer and more effective than current FDA-approved ...
Alzheimer's disease & dementia
May 17, 2013 |
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Baffling blood problem explained: 60-year-old health mystery solved
In the early 1950's, a 66-year-old woman, sick with colon cancer, received a blood transfusion. Then, unexpectedly, she suffered a severe rejection of the transfused blood. Reporting on her case, the French ...
Medical research
Mar 20, 2013 |
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Structure that edits messenger RNA transcripts defective in two different forms of motor neuron diseases
Amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA) are degenerative motor neuron diseases in which the key mutated genes are involved in RNA metabolism. This similarity suggests that a ...
Medical research
Apr 26, 2013 |
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Molecular knock-out alleviates Alzheimer's symptoms in mice
Researchers at the German Center for Neurodegenerative Diseases (DZNE) and the University Medical Center Göttingen (UMG) have identified an enzyme as a possible target for the treatment of Alzheimer's disease. The protein ...
Alzheimer's disease & dementia
Nov 30, 2012 |
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Researchers identify new pathway, enhancing tamoxifen to tame aggressive breast cancer
Tamoxifen is a time-honored breast cancer drug used to treat millions of women with early-stage and less-aggressive disease, and now a University of Rochester Medical Center team has shown how to exploit tamoxifen's secondary ...
Cancer
Apr 23, 2013 |
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One gene predicts rapid ALS progression 80 percent of the time
(Medical Xpress)—The debilitating symptoms of amyotrophic lateral sclerosis, or ALS, appear to be increased by a lack of inflammation-reducing T cells, report scientists from the Methodist Neurological Institute in an upcoming ...
Genetics
Dec 10, 2012 |
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Scientists reveal how natural antibiotic kills tuberculosis bacterium
A natural product secreted by a soil bacterium shows promise as a new drug to treat tuberculosis report scientists in a new study published in EMBO Molecular Medicine. A team of scientists working in Switzerland has shown ...
Diseases, Conditions, Syndromes
Sep 17, 2012 |
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Sequencing tracks animal-to-human transmission of bacterial pathogens
Researchers have used whole genome sequencing to reveal if drug-resistant bacteria are transmitted from animals to humans in two disease outbreaks that occurred on different farms in Denmark. The results, which are published ...
Genetics
Mar 25, 2013 |
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Stem cells boost heart's natural repair mechanisms
Injecting specialized cardiac stem cells into a patient's heart rebuilds healthy tissue after a heart attack, but where do the new cells come from and how are they transformed into functional muscle?
Medical research
Jan 30, 2013 |
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Liver controls wasting in cancer: Overactive gene switch in the liver causes blood fat levels to drop
Many cancer patients suffer from a dramatic loss of fat and muscle mass. This extreme wasting, or cachexia, is often the actual cause of death in cancer patients. Heidelberg scientists have now discovered in mice that tumors ...
Cancer
Jan 14, 2013 |
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Monocyte migrations
LMU researchers led by Christian Weber have, for the first time, elucidated how cells that promote the development of atherosclerosis find their way to the blood vessel wall, where they stimulate the formation of obstructive ...
Medical research
Feb 19, 2013 |
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Producing new neurones under all circumstances: A challenge that is just a mouse away
Improving neurone production in elderly persons presenting with a decline in cognition is a major challenge facing an ageing society and the emergence of neuro-degenerative conditions such as Alzheimer's disease. INSERM and ...
Medical research
Apr 09, 2013 |
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Biologists achieve repair and read-through of stop mutations responsible for Usher syndrome
After years of basic research, scientists at Johannes Gutenberg University Mainz (JGU) are increasingly able to understand the mechanisms underlying the human Usher syndrome and are coming ever closer to ...
Genetics
Dec 04, 2012 |
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A urine test for Kawasaki disease
A set of proteins detected in urine by researchers at Boston Children's Hospital may prove to be the first biomarkers for Kawasaki disease, an uncommon but increasingly prevalent disease which causes inflammation of blood ...
Diseases, Conditions, Syndromes
Dec 20, 2012 |
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Turning off key piece of genetic coding eliminates toxic effect of statins
In research funded by the National Institutes of Health and the American Heart Association and published in EMBO Molecular Medicine, Saint Louis University investigator Ángel Baldán, Ph.D., found that the microR ...
Medical research
Jul 09, 2012 |
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