Genes & Development
'Junk DNA' drives embryonic development
An embryo is an amazing thing. From just one initial cell, an entire living, breathing body emerges, full of working cells and organs. It comes as no surprise that embryonic development is a very carefully ...
Genetics
Dec 03, 2012 |
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Study IDs key protein for cell death, offers way to kill cancer cells by forcing them into programmed-death pathway
When cells suffer too much DNA damage, they are usually forced to undergo programmed cell death, or apoptosis. However, cancer cells often ignore these signals, flourishing even after chemotherapy drugs have ...
Genetics
May 14, 2013 |
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Researchers discover that errors in RNA splicing lead to a class of neurological disorders
(Medical Xpress)—Researchers have found that missteps in a basic cellular process, RNA splicing, is the culprit behind a class of rare neurological disorders manifested by intellectual disability and stunted development.
Genetics
Mar 29, 2013 |
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Cell reprogramming during liver regeneration
During embryonic development, animals generate many different types of cells, each with a distinct function and identity.
Medical research
Mar 28, 2013 |
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Cellular renewal process may underlie benefits of omega fatty acids
A search for genes that change their levels of expression in response to nutrient deprivation has uncovered potential clues to the mechanism underlying the health benefits of omega fatty acids. In the Feb. 15 issue of Genes & ...
Health
Feb 13, 2013 |
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Study offers clues to cause of kids' brain tumors
(Medical Xpress)—Insights from a genetic condition that causes brain cancer are helping scientists better understand the most common type of brain tumor in children.
Genetics
Nov 16, 2012 |
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Unlocking the destiny of a cell
(Medical Xpress)— Scientists have discovered that breaking a biological signaling system in an embryo allows them to change the destiny of a cell. The findings could lead to new ways of making replacement ...
Genetics
Nov 01, 2012 |
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Researchers reveal how Trop2 protein drives tumor growth in prostate, other epithelial cancers
(Medical Xpress)—Researchers led by Tanya Stoyanova and Dr. Owen Witte of UCLA's Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research have determined how a protein known as Trop2 drives the growth ...
Cancer
Oct 16, 2012 |
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New insights on control of pituitary hormone outside of brain has implications for breast cancer
The hormone prolactin is produced by the pituitary gland in the brain and then travels via the bloodstream to cells throughout the body, where it exerts multiple reproductive and metabolic effects, most notably ...
Genetics
Oct 01, 2012 |
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Study pinpoints epigenetic function of common cancer-causing protein—it's not what science thought
(Medical Xpress)—Squamous cell carcinoma (SCC) is diagnosed in about 700,000 people in the United States every year. Commonly contributing to SCC is a protein called DNp63a – it goes abnormally high and the ability of ...
Genetics
Sep 26, 2012 |
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Protein found to regulate red blood cell size and number
The adult human circulatory system contains between 20 and 30 trillion red blood cells (RBCs), the precise size and number of which can vary from person to person. Some people may have fewer, but larger RBCs, while others ...
Genetics
Aug 28, 2012 |
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Team introduces new method to closely model diseases caused by splicing defects
A team led by scientists at Cold Spring Harbor Laboratory (CSHL) has developed a new way of making animal models for a broad class of human genetic diseases – those with pathology caused by errors in the splicing of ...
Genetics
Aug 14, 2012 |
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Study suggests patients should be screened before receiving vemurafenib
Different genetic mistakes driving skin cancer may affect how patients respond to the drug vemurafenib, providing grounds to screen people with melanoma skin cancer before treatment, a new study by Cancer Research UK scientists ...
Cancer
Aug 14, 2012 |
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Protein involved in DNA replication, centrosome regulation linked to dwarfism, small brain size
Research published Aug. 1 by scientists at Cold Spring Harbor Laboratory (CSHL) links gene mutations found in some patients with Meier-Gorlin syndrome (MGS) with specific cellular dysfunctions that are thought to give rise ...
Genetics
Jul 31, 2012 |
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The influence of the mother: Maternal epigenetic inheritance
(Medical Xpress) -- A study published in Genes and Development from scientists at the Friedrich Miescher Institute for Biomedical Research pinpoints the importance of maternal epigenetic influences during ...
Genetics
May 07, 2012 |
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