Genes & Development

Genetics

Researchers identify DNA elements that affect MECP2 expression

Researchers at Baylor College of Medicine and the Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital (NRI) have identified and characterized two regions of DNA required for the proper expression ...

Medical research

Discovery illuminates how thyroid hormone 'dims' metabolism

It has been known for some time that the thyroid gland is a strong regulator of the body's metabolism, making it key to many health conditions. But the molecular details of how thyroid hormone acts on cells in the body have ...

Oncology & Cancer

Mutation leading to biological changes may play role in cancer

A new study from McGill University's Goodman Cancer Research Center (GCRC) has revealed significant biological changes in mice expressing an activated, mutant form of the Estrogen Receptor alpha (ER alpha), shedding new light ...

Genetics

Novel approach reduces SCA1 symptoms in animal model

Research has shown that a mutation in the ATAXIN-1 gene leads to accumulation of Ataxin-1 (ATXN1) protein in brain cells and is the root cause of a rare genetic neurodegenerative disease known as spinocerebellar ataxia type ...

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