Metastatic ovarian, prostate and breast cancers are notoriously difficult to treat and often deadly. Now, Salk Institute researchers have revealed a new role for the CDK12 protein. The findings were published in the print ...
Apr 3, 2019
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71
When a muscle grows or a muscle injury heals, some stem cells develop into new muscle cells. A research team at the MDC led by Carmen Birchmeier has now described in the journal Genes & Development how this process is regulated ...
Mar 18, 2019
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52
Northwestern Medicine scientists have discovered two successful therapies that slowed the progression of pediatric leukemia in mice, according to three studies published over the last two years in the journal Cell, and the ...
Dec 21, 2018
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55
A newfound genetic regulatory mechanism may shape the immune system's ability to fight viral infections, and play a key role in autoimmune diseases that occur when immune cells attack bodily tissues.
Nov 27, 2018
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112
Melbourne scientists have discovered how tumour development is driven by mutations in the most important gene in preventing cancer, p53.
Nov 7, 2018
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163
Forty years after researchers first discovered it in fruit flies, a once-obscure cluster of proteins called PRC2 has become a key target for new cancer-fighting drugs, due to its tendency—when mutated—to bind to and silence ...
Jun 15, 2018
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122
Our bodies are not just passively growing older. Cells and tissues continuously use information from our environments—and from each other—to actively coordinate the aging process. A new study from the University of Michigan ...
Feb 28, 2018
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256
The process by which embryonic stem cells develop into heart cells is a complex process involving the precisely timed activation of several molecular pathways and at least 200 genes. Now, Salk Institute scientists have found ...
Dec 21, 2017
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64
Scientists have long sought to unravel the molecular mysteries that make the human brain special: What processes drove its evolution through the millennia? Which genes are critical to cognitive development?
Dec 6, 2017
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690
Northwestern Medicine scientists have discovered that a protein called BRWD2/PHIP binds to histone lysine 4 (H3K4) methylation—a key molecular event that influences gene expression—and demonstrated that it does so via ...
Nov 10, 2017
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