Journal of Biological Chemistry

Breakthrough in understanding human immune response has potential for the development of new drug therapies

(Medical Xpress) -- A team of researchers at Trinity College Dublin’s School of Medicine has gained new insights into a protein in the human immune system that plays a key role in the protective response to infection ...

Immunology created Jul 06, 2012 | popularity 5 / 5 (6) | comments 0 | with audio podcast

Researchers closer to understanding how proteins regulate immune system

Researchers in the biological sciences department in the Faculty of Science at the University of Calgary have revealed how white blood cells move to infection or inflammation in the body; findings which could help lead to ...

Immunology created Jul 03, 2012 | popularity not rated yet | comments 0 | with audio podcast

Exercise is key in the fight against Alzheimer's disease

In a recent Journal of Biological Chemistry "Paper of the Week," research led by Ayae Kinoshita at the Kyoto University Graduate School of Medicine in Japan reveals the benefits of exercise in combating Alzheimer's diseas ...

Alzheimer's disease & dementia created Jun 27, 2012 | popularity 5 / 5 (2) | comments 0

Prions and cancer: A story unfolding

Prions, the causal agents of Mad Cow and other diseases, are very unique infectious particles. They are proteins in which the complex molecular three-dimensional folding process just went astray. For reasons not yet understood, ...

Cancer created Jun 25, 2012 | popularity 5 / 5 (1) | comments 0

Investigational diabetes drug may have fewer side effects

Drugs for type 2 diabetes can contribute to weight gain, bone fractures and cardiovascular problems, but in mice, an investigational drug appears to improve insulin sensitivity without those troublesome side ...

Medical research created Jun 04, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

New finding important to heart health, also changed faculty member's entire research path

Medical scientist Howard Young's research has taken a dramatic, unexpected turn in the last few months, thanks to a serendipitous chain of events that could lead to a genetic test that can predict heart failure in certain ...

Medical research created Jun 01, 2012 | popularity not rated yet | comments 0

Is there a 'healthy' obesity gene?

Why is it that some obese people are healthier than others? This was one of the main questions Dr. Chaodong Wu of the College of Agriculture and Life Sciences — Texas A&M University System — and a group of researchers ...

Genetics created May 31, 2012 | popularity not rated yet | comments 0 | with audio podcast

Breast stem-cell research: Receptor teamwork is required and a new pathway may be involved

Breast-cancer researchers at the University of Wisconsin-Madison have found that two related receptors in a robust signaling pathway must work together as a team to maintain normal activity in mammary stem cells.

Cancer created May 30, 2012 | popularity not rated yet | comments 0 | with audio podcast

Aggregating instead of stabilizing: New insights into the mechanisms of heart disease

Malformed desmin proteins aggregate with intact proteins of the same kind, thereby triggering skeletal and cardiac muscle diseases, the desminopathies. This was discovered by researchers from the RUB Heart and Diabetes Center ...

Medical research created May 23, 2012 | popularity not rated yet | comments 0

Neuron-nourishing cells appear to retaliate in Alzheimer's

When brain cells start oozing too much of the amyloid protein that is the hallmark of Alzheimer's disease, the astrocytes that normally nourish and protect them deliver a suicide package instead, researchers ...

Alzheimer's disease & dementia created May 22, 2012 | popularity not rated yet | comments 0 | with audio podcast

'Next Generation' cancer treatment ready for clinical trials

(Medical Xpress) -- A new class of anti-cancer drugs which control the growth and spread of cancers and do so with minimal side effects is being developed by researchers at the University of Sydney.

Cancer created May 18, 2012 | popularity 4.7 / 5 (3) | comments 0

Professor links gene mutations with heart disease precursors

(Medical Xpress) -- It may be easier in the future to test and potentially provide early treatment for the one in 500 people affected by hypertrophic cardiomyopathy.

Cardiology created May 17, 2012 | popularity not rated yet | comments 0 | with audio podcast

Researchers identify potential target for anthrax drug

(Medical Xpress) -- Researchers at the University of Michigan have identified new targets for drugs that could potentially treat anthrax, the deadly infection caused by Bacillus anthracis.

Medical research created May 09, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Researchers find potential 'dark side' to diets high in beta-carotene

New research suggests that there could be health hazards associated with consuming excessive amounts of beta-carotene.

Health created May 01, 2012 | popularity not rated yet | comments 0 | with audio podcast

Researchers have identified a gene with a key role in neuronal survival

Spanish researchers at the Institute of Neurosciences at Universitat Autonoma de Barcelona (INc-UAB) identified the fundamental role played by the Nurr1 gene in neuron survival associated with synaptic activity. The discovery, ...

Neuroscience created Apr 16, 2012 | popularity 5 / 5 (1) | comments 0