Journal of Biological Chemistry

Vicious cycle: Obesity sustained by changes in brain biochemistry

With obesity reaching epidemic levels in some parts of the world, scientists have only begun to understand why it is such a persistent condition. A study in the Journal of Biological Chemistry adds substantially to the st ...

Medical research created May 16, 2013 | popularity 3 / 5 (2) | comments 2 | with audio podcast

Bacteria may contribute to premature births, STDs

(Medical Xpress)—New research at Washington University School of Medicine in St. Louis points to a common species of bacteria as an important contributor to bacterial vaginosis, a condition linked to preterm ...

Medical research created Apr 23, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Increased stability of a misfolded protein linked to age of onset of common form of motor neuron disease

Neurodegenerative diseases are characterized by the aggregation of misfolded proteins, which accumulate to form insoluble clumps within or around nerve cells. In the adult motor neuron disease amyotrophic ...

Medical research created Apr 22, 2013 | popularity 5 / 5 (1) | comments 0

Study finds new drug target for metastatic breast cancer

Research led by Dr. Suresh Alahari, Professor of Biochemistry and Molecular Biology at LSU Health Sciences Center New Orleans, is the first to report that two specific tumor suppressor genes work in concert to inhibit the ...

Cancer created Apr 11, 2013 | popularity 5 / 5 (1) | comments 0

Study reveals Rx target for HPV, Hep C and related cancers

New discoveries by a team of scientists at LSU Health Sciences Center New Orleans for the first time reveal the inner workings of a master regulator that controls functions as diverse as the ability of nerve cells to "rewire" ...

Medical research created Apr 10, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Landmark study describes prostate cancer metastasis switch

Prostate cancer doesn't kill in the prostate – it's only once the disease travels to bone, lung, liver, etc. that it turns fatal. Previous studies have shown that loss of the protein E-Cadherin is essential for this metastasis. ...

Cancer created Apr 02, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Parkinson's disease protein gums up garbage disposal system in cells

(Medical Xpress)—Clumps of α-synuclein protein in nerve cells are hallmarks of many degenerative brain diseases, most notably Parkinson's disease.

Parkinson's & Movement disorders created Mar 28, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Scientists identify Buphenyl as a possible drug for Alzheimer's disease

(Medical Xpress)—Buphenyl, an FDA-approved medication for hyperammonemia, may protect memory and prevent the progression of Alzheimer's disease. Hyperammonemia is a life-threatening condition that can affect patients at ...

Alzheimer's disease & dementia created Mar 11, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Cell sugar concentrations affect hyaluronan production and cancer growth

According to a recent University of Eastern Finland (UEF) study, elevated cell sugar concentrations increase the production of hyaluronan which, in turn, promotes cancer growth. Regulating the production ...

Cancer created Feb 27, 2013 | popularity not rated yet | comments 0

Researchers discover protein that may control the spread of cancer

Researchers at the University of Hawai'i Cancer Center have uncovered a novel mechanism that may lead to more selective ways to stop cancer cells from spreading. Associate Professor Joe W. Ramos PhD, a cancer biologist at ...

Cancer created Feb 26, 2013 | popularity 5 / 5 (1) | comments 0

Indian plant could play key role in death of cancer cells

Scientists at the Georgia Regents University Cancer Center have identified an Indian plant, used for centuries to treat inflammation, fever and malaria, that could help kill cancer cells.

Cancer created Feb 14, 2013 | popularity 4.3 / 5 (3) | comments 0 | with audio podcast

Compound developed by scientists protects heart cells during and after attack

Using two different compounds they developed, scientists from the Florida campus of The Scripps Research Institute (TSRI) have been able to show in animal models that inhibiting a specific enzyme protects heart cells and ...

Cardiology created Feb 07, 2013 | popularity 4 / 5 (1) | comments 0 | with audio podcast

Green tea and red wine extracts interrupt Alzheimer's disease pathway in cells

Natural chemicals found in green tea and red wine may disrupt a key step of the Alzheimer's disease pathway, according to new research from the University of Leeds.

Alzheimer's disease & dementia created Feb 05, 2013 | popularity 4.9 / 5 (11) | comments 0 | with audio podcast

Scientists find first human iPSC from patients with maturity onset diabetes of the young

Joslin scientists report the first generation of human induced pluripotent stem cells from patients with an uncommon form of diabetes, maturity onset diabetes of the young (MODY). These cells offer a powerful resource for ...

Medical research created Jan 31, 2013 | popularity not rated yet | comments 0

DNA-repairing protein may be key to preventing recurrence of some cancers

Just as the body can become resistant to antibiotics, certain methods of killing cancer tumors can end up creating resistant tumor cells. But a University of Central Florida professor has found a protein ...

Cancer created Jan 28, 2013 | popularity 5 / 5 (4) | comments 0 | with audio podcast