Journal of Biological Chemistry

Oncology & Cancer

Key protein in prostate cancer energy production identified

Scientists at The Wistar Institute have demonstrated how a protein called TRAP1 - an important regulator of energy production in healthy and cancerous cells - is an important driver of prostate cancer and appears to be a ...

Parkinson's & Movement disorders

Breakthrough in understanding Parkinson's disease

Research from The University of Queensland could lead to a new treatment for Parkinson's disease, with future potential applications to nearly 50 other disorders.

Genetics

Selective protection of genetic information by epigenetic system

DNA is replicated to pass genetic information to the daughter cells during cell proliferation. Replication errors, if not repaired, can lead to genetic mutations. For an individual organism, some DNA mutations may cause disease, ...

Oncology & Cancer

Study may lead to better breast cancer drugs

Biomedical scientists have revealed the inner workings of a group of proteins that help to switch critical genes on and off during blood-cell production, in a finding that could lead to the development of new and improved ...

Medical research

Study identifies potential new avenue for treating pompe disease

Researchers at Duke Health have identified a potential new avenue for treating Pompe disease, a rare condition caused by the build-up of glycogen, a storage form of sugar, in cardiac and skeletal muscle, the liver and other ...

Medical research

Discovery could lead to treatment to better regulate insulin

Medication can help trigger the enzyme that kick starts insulin production in the body, but the drugs don't always work for those who are obese or diabetic, and most need to regulate their glucose and insulin levels. That's ...

Immunology

Effect of cholesterol medicine on inflammatory diseases mapped

The cholesterol medicine simvastatin, which is one of the most commonly used pharmaceuticals in the world, also has a beneficial effect on the immune defence system with regard to diseases such as type 1 diabetes, multiple ...

page 11 from 19