Journal of Biological Chemistry

Breast stem-cell research: Receptor teamwork is required and a new pathway may be involved

Breast-cancer researchers at the University of Wisconsin-Madison have found that two related receptors in a robust signaling pathway must work together as a team to maintain normal activity in mammary stem cells.

Cancer created May 30, 2012 | popularity not rated yet | comments 0 | with audio podcast

Scientists shed new light on link between 'killer cells' and diabetes

Killer T-cells in the human body which help protect us from disease can inadvertently destroy cells that produce insulin, new research has uncovered.

Medical research created Jan 15, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Study reveals active site of enzyme linked to stuttering

(Medical Xpress)—Scientists from the Joint Center for Structural Genomics (JCSG) at SLAC National Accelerator Laboratory have determined the 3-D structure of the chemically active part of an enzyme involved ...

Medical research created May 23, 2013 | popularity 5 / 5 (5) | comments 0 | with audio podcast

Research uncovers a potential role of two proteins in diabetes

(Medical Xpress)—Flinders University researchers are breaking new ground in a decade-long journey to pinpoint the function of two closely related proteins.

Diabetes created May 20, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Vicious cycle: Obesity sustained by changes in brain biochemistry

With obesity reaching epidemic levels in some parts of the world, scientists have only begun to understand why it is such a persistent condition. A study in the Journal of Biological Chemistry adds substantially to the st ...

Medical research created May 16, 2013 | popularity 3 / 5 (2) | comments 2 | with audio podcast

Bacteria may contribute to premature births, STDs

(Medical Xpress)—New research at Washington University School of Medicine in St. Louis points to a common species of bacteria as an important contributor to bacterial vaginosis, a condition linked to preterm ...

Medical research created Apr 23, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Study reveals Rx target for HPV, Hep C and related cancers

New discoveries by a team of scientists at LSU Health Sciences Center New Orleans for the first time reveal the inner workings of a master regulator that controls functions as diverse as the ability of nerve cells to "rewire" ...

Medical research created Apr 10, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Landmark study describes prostate cancer metastasis switch

Prostate cancer doesn't kill in the prostate – it's only once the disease travels to bone, lung, liver, etc. that it turns fatal. Previous studies have shown that loss of the protein E-Cadherin is essential for this metastasis. ...

Cancer created Apr 02, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Parkinson's disease protein gums up garbage disposal system in cells

(Medical Xpress)—Clumps of α-synuclein protein in nerve cells are hallmarks of many degenerative brain diseases, most notably Parkinson's disease.

Parkinson's & Movement disorders created Mar 28, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Scientists identify Buphenyl as a possible drug for Alzheimer's disease

(Medical Xpress)—Buphenyl, an FDA-approved medication for hyperammonemia, may protect memory and prevent the progression of Alzheimer's disease. Hyperammonemia is a life-threatening condition that can affect patients at ...

Alzheimer's disease & dementia created Mar 11, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Indian plant could play key role in death of cancer cells

Scientists at the Georgia Regents University Cancer Center have identified an Indian plant, used for centuries to treat inflammation, fever and malaria, that could help kill cancer cells.

Cancer created Feb 14, 2013 | popularity 4.3 / 5 (3) | comments 0 | with audio podcast

Compound developed by scientists protects heart cells during and after attack

Using two different compounds they developed, scientists from the Florida campus of The Scripps Research Institute (TSRI) have been able to show in animal models that inhibiting a specific enzyme protects heart cells and ...

Cardiology created Feb 07, 2013 | popularity 4 / 5 (1) | comments 0 | with audio podcast

Green tea and red wine extracts interrupt Alzheimer's disease pathway in cells

Natural chemicals found in green tea and red wine may disrupt a key step of the Alzheimer's disease pathway, according to new research from the University of Leeds.

Alzheimer's disease & dementia created Feb 05, 2013 | popularity 4.9 / 5 (11) | comments 0 | with audio podcast

DNA-repairing protein may be key to preventing recurrence of some cancers

Just as the body can become resistant to antibiotics, certain methods of killing cancer tumors can end up creating resistant tumor cells. But a University of Central Florida professor has found a protein ...

Cancer created Jan 28, 2013 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Scientists identify new strategy to fight deadly infection in cystic fibrosis

New research suggests that lowering excessive levels of a protein in immune system cells could be a strategy to clear an infection that is deadly to patients with cystic fibrosis (CF).

Medical research created Jan 23, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast