Journal of Cell Biology

Diseases, Conditions, Syndromes

Protein study may be key to treating fibrotic diseases

A protein linked to amyotrophic lateral sclerosis (ALS), a progressive neurological disease that causes muscle weakness, may be a key to treating fibrotic disease of the kidneys and other organs, researchers at Vanderbilt ...

Medical research

A firmer understanding of muscle fibrosis

Researchers describe how increased production of a microRNA promotes progressive muscle deterioration in a mouse model of Duchenne muscular dystrophy (DMD), according to a study published online on January 2 in the Journal ...

Medical research

Biologists identify mechanisms of embryonic wound repair

It's like something out of a science-fiction movie - time-lapse photography showing how wounds in embryos of fruit flies heal themselves. The images are not only real; they shed light on ways to improve wound recovery in ...

Parkinson's & Movement disorders

Function of gene mutations linked to neurological diseases identified

Several gene mutations have been linked to Parkinson's disease, but exactly how and where some of them cause their damage has been unclear. A new Yale study, published in the Journal of Cell Biology, shows that one of the ...

Medical research

Study identifies molecule critical to healing wounds

Skin provides a first line of defense against viruses, bacteria and parasites that might otherwise make people ill. When an injury breaks that barrier, a systematic chain of molecular signaling launches to close the wound ...

HIV & AIDS

Study reveals how a Rab protein controls HIV-1 replication

HIV-1 replication requires the coordinated movement of the virus's components toward the plasma membrane of an immune cell, where the virions are assembled and ultimately released. A study in The Journal of Cell Biology reveals ...

Medical research

Can our bones protect us against diabetes and obesity?

A team of researchers at the IRCM led by Mathieu Ferron, PhD, in collaboration with researchers at Columbia University, discovered a new function of the skeleton associated with diabetes and obesity. The scientific breakthrough, ...

Medical research

Slowed cell division causes microcephaly

The birth of a human being requires billions of cell divisions to go from a fertilized egg to a baby. At each of these divisions, the genetic material of the mother cell duplicates itself to be equally distributed between ...

Neuroscience

A new view for protein turnover in the brain

Keeping the human brain in a healthy state requires a delicate balance between the generation of new cellular material and the destruction of old. Specialized structures known as lysosomes, found in nearly every cell in your ...

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