Journal of Clinical Investigation
Enhanced brain acetate metabolism may reward heavy drinkers
In addition to its well-known effects on the CNS, alcohol consumption has a significant impact on metabolism. After consumption, the body rapidly begins converting ethanol to acetate, which can serve as an energy source for ...
Addiction
Mar 08, 2013 |
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Full wired: Planar cell polarity genes guide gut neurons
The enteric nervous system (ENS), the "little brain" that resides within the gut wall, governs motility, secretion, and blood flow in the human gastrointestinal tract. Failure of the ENS to develop normally leads to congenital ...
Medical research
Mar 08, 2013 |
4.5 / 5 (2) |
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Tumors deliberately create conditions that inhibit body's best immune response
New research in the Journal of Clinical Investigation reveals that tumours in melanoma patients deliberately create conditions that knock out the body's 'premier' immune defence and instead attract a weaker immune respon ...
Cancer
Mar 01, 2013 |
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A better bone marrow transplant: Preventing graft-versus-host disease
Bone marrow transplant is a key treatment for patients with leukemia, lymphoma, multiple myeloma and other blood disorders.
Medical research
Mar 01, 2013 |
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A nanogel-based treatment for lupus
Systemic lupus erythematosus (SLE) is disease in which the immune system mistakenly attacks healthy tissues, resulting in inflammation and tissue damage. Current treatments are focused on suppression of the immune system, ...
Diseases, Conditions, Syndromes
Mar 01, 2013 |
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A coordinated response to cardiac stress
Myocardial hypertrophy, a thickening of the heart muscle, is an adaptation that occurs with increased stress on the heart, such as high blood pressure. As the heart muscle expands, it also requires greater blood flow to maintain ...
Cardiology
Mar 01, 2013 |
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Scientists find way to image brain waste removal process, may lead to Alzheimer's diagnostic
(Medical Xpress)—A novel way to image the entire brain's glymphatic pathway, a dynamic process that clears waste and solutes from the brain that otherwise might build-up and contribute to the development ...
Neuroscience
Feb 25, 2013 |
5 / 5 (1) |
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Reprogramming cells to fight diabetes
For years researchers have been searching for a way to treat diabetics by reactivating their insulin-producing beta cells, with limited success. The "reprogramming" of related alpha cells into beta cells ...
Medical research
Feb 22, 2013 |
4.5 / 5 (8) |
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Pulmonary fibrosis: Between a ROCK and a hard place
Pulmonary fibrosis is a scarring or thickening of the lungs that causes shortness of breath, a dry cough, fatigue, chest discomfort, weight loss, a decrease in the ability of the lungs to transmit oxygen to the blood stream, ...
Medical research
Feb 22, 2013 |
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How to mend a broken heart: Advances in parthenogenic stem cells
Parthenogenesis is a form of asexual reproduction during which unfertilized eggs begin to develop as if they had been fertilized. It occurs naturally in many plants and a few invertebrate (some bees, scorpions, parasitic ...
Medical research
Feb 22, 2013 |
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Study finds possible link between diabetes and increased risk of heart attack death
Having diabetes doubles a person's risk of dying after a heart attack, but the reason for the increased risk is not clear. A new University of Iowa study suggests the link may lie in the over-activation of an important heart ...
Cardiology
Feb 15, 2013 |
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Scientists find promising new approach to preventing progression of breast cancer
February 15, 2013 – Doctors currently struggle to determine whether a breast tumor is likely to shift into an aggressive, life-threatening mode—an issue with profound implications for treatment. Now a group from The Scripps ...
Cancer
Feb 15, 2013 |
4.6 / 5 (5) |
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Key molecule suppresses growth of cancerous liver tumors, study finds
(Medical Xpress)—A molecule already implicated in a number of diverse cellular functions can suppress the growth of tumors in the liver, a Mayo Clinic Cancer Center study has found. Its name is IQGAP1, and when the molecule ...
Cancer
Feb 13, 2013 |
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New insight into RASopathy-associated lymphatic defects
The RAS pathway is a cellular signaling pathway that regulates growth and development in humans. RASopathies are a group of diseases characterized by defects in RAS signaling.
Diseases, Conditions, Syndromes
Feb 08, 2013 |
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New strategy prevents rheumatoid arthritis in mice
Dana-Farber Cancer Institute scientists have demonstrated a new strategy for treating autoimmune disease that successfully blocked the development of rheumatoid arthritis in a mouse model. They say it holds promise for improved ...
Arthritis & Rheumatism
Feb 08, 2013 |
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