Journal of Clinical Investigation
Tumors deliberately create conditions that inhibit body's best immune response
New research in the Journal of Clinical Investigation reveals that tumours in melanoma patients deliberately create conditions that knock out the body's 'premier' immune defence and instead attract a weaker immune respon ...
Cancer
Mar 01, 2013 |
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Study identifies biological mechanism that plays key role in early-onset dementia
Using animal models, scientists at the Gladstone Institutes have discovered how a protein deficiency may be linked to frontotemporal dementia (FTD)—a form of early-onset dementia that is similar to Alzheimer's disease. ...
Neuroscience
Oct 08, 2012 |
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Research finds key molecules involved in forming long-term memories
How does one's experience of an event get translated into a memory that can be accessed months, even years later? A team led by University of Pennsylvania scientists has come closer to answering that question, identifying ...
Medical research
Sep 10, 2012 |
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Deadly liver cancer may be triggered by cells changing identity, study shows
A rare type of cancer thought to derive from cells in the bile ducts of the liver may actually develop when one type of liver cell morphs into a totally different type, a process scientists used to consider all but impossible. ...
Cancer
Jul 16, 2012 |
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Surprising culprit behind chemo resistance in rare cancer
Researchers at Washington University School of Medicine in St. Louis have shown how an aggressive form of multiple myeloma resists chemotherapy.
Cancer
Jul 02, 2012 |
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Mystery gene reveals new mechanism for anxiety disorders
A novel mechanism for anxiety behaviors, including a previously unrecognized inhibitory brain signal, may inspire new strategies for treating psychiatric disorders, University of Chicago researchers report.
Genetics
May 15, 2012 |
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Mini molecules could help fight battle of aortic bulge
When aortic walls buckle, the body's main blood pipe forms an ever-growing bulge. To thwart a deadly rupture, a team of Stanford University School of Medicine researchers has found two tiny molecules that may be able to orchestrate ...
Cardiology
Feb 22, 2012 |
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Going live: Immune cell activation in multiple sclerosis
Biological processes are generally based on events at the molecular and cellular level. To understand what happens in the course of infections, diseases or normal bodily functions, scientists would need to ...
Immunology
7 hours ago |
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Transplant experts challenge assumption, describe pathway that leads to organ rejection
Transplant researchers at the University of Pittsburgh School of Medicine challenge a long-held assumption about how biologic pathways trigger immune system rejection of donor organs in a report published online today in ...
Medical research
May 15, 2013 |
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Differences between 'marathon mice' and 'couch potato mice' reveal key to muscle fitness
Researchers discovered that small pieces of genetic material called microRNAs link the two defining characteristics of fit muscles: the ability to burn sugar and fat and the ability to switch between slow- ...
Medical research
May 08, 2013 |
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Baby knows best: Fetuses emit hormone crucial to preventing preeclampsia
In a study using mice, researchers from the University of North Carolina at Chapel Hill found that a hormone, adrenomedullin, plays a crucial role in preventing the pregnancy complication preeclampsia. Surprisingly, ...
Medical research
May 01, 2013 |
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Rare, lethal childhood disease tracked to protein
A team of international researchers led by Northwestern Medicine scientists has identified how a defective protein plays a central role in a rare, lethal childhood disease known as Giant Axonal Neuropathy, or GAN. The finding ...
Medical research
Apr 29, 2013 |
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Firefly protein lights up degenerating muscles, aiding muscular-dystrophy research
Stanford University School of Medicine scientists have created a mouse model of muscular dystrophy in which degenerating muscle tissue gives off visible light. The observed luminescence occurs only in damaged muscle tissue ...
Medical research
Apr 24, 2013 |
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Transcription factors regulating blood oxygen linked to melanoma metastases
Researchers at the University of North Carolina have discovered that transcription factors regulating the levels of oxygen in the blood also play a role in the spread of the skin cancer melanoma.
Cancer
Apr 16, 2013 |
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Brain-building gene plays key role in gut repair
(Medical Xpress)—A gene with a colorful name – mindbomb 1 – plays a key role far beyond the brain. New research at Washington University School of Medicine in St. Louis shows that mindbomb 1 may be ...
Genetics
Apr 05, 2013 |
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