Antibiotics are known to upset the balance of bacteria in the intestinal tract. In some cases, antibiotics can cause the bacterium Clostridium difficile (C. difficile) to overgrow wildly, causing diarrhea and, in severe cases, ...
Aug 15, 2019
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Five years ago, David C. Fajgenbaum, MD, MBA, MSc, both a Penn Medicine researcher and patient, tried an experimental treatment on himself based on his laboratory research findings in the hopes of saving his own life. He ...
Aug 13, 2019
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Anaphylactic shock, an exacerbated allergic reaction that can prove fatal, is sometimes caused by the use of drugs during surgery. In most of these extreme reactions, evidence can be provided that patients have anti-drug ...
Jul 10, 2019
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Shikhar Mehrotra, Ph.D. and Xue-Zhong Yu, M.D., National Institutes of Health-funded researchers at the Medical University of South Carolina (MUSC), have discovered a way to improve immune-based treatments, such as adoptive ...
Jul 8, 2019
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An anti-inflammatory drug called ketorolac, given before surgery, can promote long-term survival in animal models of cancer metastasis, a team of scientists has found. Furthermore, so-called "pro-resolution" therapies can ...
Jun 18, 2019
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Regardless of how much you exercise or how balanced your diet is, controlling your weight is more brain-related than you might have thought. In a study published in the Journal of Clinical Investigation, researchers from ...
May 13, 2019
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Researchers report that a protein known to be important to protein synthesis also influences muscle regeneration and regrowth in an unexpected manner. The discovery, reported in the Journal of Clinical Investigation, could ...
May 6, 2019
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A new study provides critical insight into a little-known, yet relatively common, inherited neurological condition called Charcot-Marie-Tooth disease. The findings point to a pathway to possible treatments for this disease ...
Apr 4, 2019
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Food allergies, celiac disease, inflammatory bowel disease (IBD), diarrhea and other gastrointestinal diseases have something in common: all have been linked to epithelial barrier loss. The gut epithelial barrier—that critical ...
Apr 1, 2019
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Precision cancer drugs called PARP inhibitors have a previously unknown ability to boost the immune system, and could help many more patients benefit from immunotherapy, a new study reveals.
Mar 9, 2019
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