Journal of Clinical Oncology

Psychoeducational intervention changes patient attitudes on clinical trials participation

Seeking ways to change cancer patients' perceptions and negative attitudes towards clinical trials participation, researchers at Moffitt Cancer Center conducted a study offering two different kinds of intervention to two ...

Cancer created Jun 13, 2012 | popularity not rated yet | comments 0

Combination therapy for triple-negative breast cancer disappointing

(Medical Xpress) -- A recent clinical trial testing a combination therapy for basal-like (also known as triple-negative) breast cancer demonstrates that a combination of two drugs with promising preclinical ...

Cancer created Jun 13, 2012 | popularity not rated yet | comments 0 | with audio podcast

Marker distinguishes more-aggressive from less-aggressive forms of chronic leukemia

Researchers have identified a prognostic marker in the most common form of chronic leukemia that can help to distinguish which patients should start treatment quickly from those who can safely delay treatment, perhaps for ...

Cancer created Jun 12, 2012 | popularity not rated yet | comments 0 | with audio podcast

Diabetes drug metformin may cut breast cancer risk in older women

(HealthDay) -- A widely prescribed drug, metformin, may lower the risk of invasive breast cancer in postmenopausal women with diabetes, a new study indicates.

Cancer created Jun 11, 2012 | popularity not rated yet | comments 0

Radiation ups event-free, not overall survival in ped Hodgkin's

(HealthDay) -- For children with Hodgkin's lymphoma who respond to chemotherapy, treatment with low-dose involved-field radiation therapy (IFRT) improves event-free survival (EFS), but has no significant impact ...

Cancer created May 31, 2012 | popularity 5 / 5 (1) | comments 0

Pathologic response prediction of survival aided by tumor type

(HealthDay) -- Pathologic complete response (pCR) is more highly predictive of recurrence-free survival (RFS) when specific breast cancer tumor type is factored in, according to a study published online May ...

Cancer created May 30, 2012 | popularity not rated yet | comments 0

Obesity, overweight at diagnosis ups B-cell lymphoma prognosis

(HealthDay) -- For U.S. veterans with diffuse large B-cell lymphoma (DLBCL), being overweight or obese at time of diagnosis correlates with improved survival, according to a study published online May 29 in ...

Cancer created May 30, 2012 | popularity not rated yet | comments 0

Brentuximab vedotin effective in large-cell lymphoma

(HealthDay) -- More than half of patients with relapsed or refractory systemic anaplastic large-cell lymphoma (ALCL) treated with the CD30-directed antibody-drug conjugate brentuximab vedotin achieve a complete ...

Cancer created May 24, 2012 | popularity not rated yet | comments 0

Childhood cancer scars survivors later in life

Scars left behind by childhood cancer treatments are more than skin-deep. The increased risk of disfigurement and persistent hair loss caused by childhood cancer and treatment are associated with emotional distress and reduced ...

Cancer created May 24, 2012 | popularity not rated yet | comments 0

Regorafenib active in metastatic GI stromal tumors

(HealthDay) -- Regorafenib, an inhibitor of multiple cancer-associated kinases, is active in patients with metastatic gastrointestinal stromal tumors (GIST) who have failed to respond to imatinib and sunitinib, ...

Cancer created May 23, 2012 | popularity not rated yet | comments 0

Cardio fitness levels of breast cancer patients may affect survival

Women receiving care for breast cancer have significantly impaired cardio-pulmonary function that can persist for years after they have completed treatment, according to a study led by scientists at Duke University Medical ...

Cancer created May 23, 2012 | popularity not rated yet | comments 0 | with audio podcast

Study finds moderate weight loss reduces levels of sex hormones linked to breast cancer risk

Even a moderate amount of weight loss can significantly reduce levels of circulating estrogens that are associated with an increased risk of breast cancer, according to a study by researchers at Fred Hutchinson Cancer Research ...

Cancer created May 21, 2012 | popularity 5 / 5 (1) | comments 0

Adjuvant radiochemotherapy has lasting benefit in gastric cancer

(HealthDay) -- Ten-year data from the Southwestern Oncology Group-directed Intergroup Study 0116 confirm the benefits of adjuvant radiochemotherapy after gastric cancer resection in terms of overall survival ...

Cancer created May 18, 2012 | popularity 1 / 5 (1) | comments 0

Gene expression profile testing increasing in breast cancer

(HealthDay) -- From 2006 to 2008, the use of gene expression profile (GEP) testing increased, correlating with a decrease in the percentage of women with hormone receptor (HR)-positive breast cancer receiving ...

Cancer created May 18, 2012 | popularity 5 / 5 (1) | comments 0

Sex influences survival in esophageal cancer

(HealthDay) -- Sex is an independent prognostic factor for patients with locoregional esophageal cancer (LEC) and metastatic esophageal cancer (MEC), according to a study published online May 14 in the Journal of ...

Cancer created May 16, 2012 | popularity not rated yet | comments 0