Journal of Clinical Oncology
Hopes that new substance will induce cancer cell suicide
(Medical Xpress)—The p53 gene plays a key role in the prevention of cancer, by blocking cell growth and triggering programmed cell death or apoptosis. If, however, p53 has mutated and become defective, the cancer cells ...
Cancer
Sep 18, 2012 |
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Adding ketamine to opioids doesn't reduce cancer pain
(HealthDay)—Using subcutaneously administered ketamine in a dose-escalating regimen as an adjunct to opioids and standard co-analgesics does not have any clinical benefit in relieving cancer pain, but it ...
Cancer
Sep 11, 2012 |
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Improved diagnostic test benefits children with acute myeloid leukemia
Early treatment response is a powerful predictor of long-term outcome for young patients with acute myeloid leukemia (AML). The information can help physicians decide whether a more intensive approach is needed. Research ...
Cancer
Sep 10, 2012 |
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Neurocognitive deficits seen in survivors of pediatric Hodgkin's
(HealthDay)—Adult long-term survivors of childhood Hodgkin's lymphoma are at risk for neurocognitive impairment, according to research published online Sept. 4 in the Journal of Clinical Oncology.
Cancer
Sep 10, 2012 |
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Characteristics of long-term gastric cancer survivors ID'd
(HealthDay)—Patients with gastric and gastroesophageal junction (GEJ) cancer who survive for longer than three years after diagnosis seem to have distinct demographic and pathologic characteristics, compared ...
Cancer
Sep 07, 2012 |
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Review finds some evidence for 'chemo brain' in breast cancer survivors
(Medical Xpress)—A large meta-analysis conducted by researchers at Moffitt Cancer Center has concluded that breast cancer patients treated with chemotherapy are at risk for mild cognitive deficits after treatment. The meta-analysis, ...
Cancer
Sep 04, 2012 |
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Gene score IDs prognosis in metastatic neuroblastoma
(HealthDay)—For children with metastatic MYCN-nonamplified neuroblastoma (NBL-NA) diagnosed at age 18 months or older, increased expression of tumor-associated inflammatory genes seems to correlate with p ...
Cancer
Aug 29, 2012 |
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Cetuximab, paclitaxel combo active in urothelial cancer
(HealthDay)—The monoclonal antibody against epidermal growth factor receptor (EGFR), cetuximab, augments the antitumor activity of paclitaxel in patients with previously treated urothelial cancer, according ...
Cancer
Aug 29, 2012 |
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Daily aspirin may help fight prostate cancer, but not breast cancer
(HealthDay)—Two new studies paint a complex portrait of aspirin's impact on cancer risk and mortality, with one suggesting the drug may lower the risk of dying from prostate cancer and the other seeing ...
Cancer
Aug 27, 2012 |
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Metastatic melanoma responds to first-line interleukin-21
(HealthDay)—In the first-line treatment of metastatic melanoma, interleukin-21 (IL-21) shows an overall response rate (ORR) of 22.5 percent and warrants further study, according to research published online ...
Cancer
Aug 23, 2012 |
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Prolonged dexamethasone cuts delayed nausea after chemo
(HealthDay) -- Adding dexamethasone to prochlorperazine on days two and three, following palonosetron and dexamethasone on day one, reduces delayed nausea (DN) in patients receiving chemotherapy containing ...
Cancer
Aug 22, 2012 |
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Melanoma expert reviews unique adverse events with newly approved drug
An internationally recognized melanoma researcher at Moffitt Cancer Center and colleagues at the University of Kiel in Germany, including Axel Hauschild, M.D. and Katharina C. Kähler, M.D., have published an article ...
Cancer
Aug 22, 2012 |
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Many options, good outcomes, for early-stage follicular lymphoma
(Medical Xpress) -- A University of Rochester Medical Center study challenges treatment guidelines for early stage follicular lymphoma, concluding that six different therapies can bring a remission, particularly if the patient ...
Cancer
Aug 21, 2012 |
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No benefit seen for adjuvant oxaliplatin in stage II colon CA
(HealthDay) -- For elderly patients with colon cancer or those with stage II disease, the addition of oxaliplatin to fluorouracil with leucovorin (FL) does not seem to offer any survival benefit, according ...
Cancer
Aug 21, 2012 |
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Older women may not benefit from radiotherapy after breast surgery
A Rhode Island Hospital radiation oncologist says in a new editorial that research exploring the impact of radiotherapy in older women with low risk of breast cancer recurrence has little effect on actual clinical decisions. ...
Cancer
Aug 21, 2012 |
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