Journal of Experimental Medicine
Cocktail boosts immune cells in fighting cancer
Natural killer cells, as part of the body´s immune system, can effectively fight cancer. Unfortunately, they quickly lose their aggressiveness and hence are unable to reject solid tumors. Scientists from the German Cancer ...
Cancer
Dec 06, 2012 |
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A more complicated network than generally accepted may control maturation of B cells in the immune system
The process of blood cell development, known as hematopoiesis, gives rise to numerous different immune cell subtypes. Each of these in turn matures through a stepwise process governed by the action of transcription ...
Medical research
Nov 22, 2012 |
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Parkinson's disease protein causes disease spread and neuron death in healthy animals
Understanding how any disease progresses is one of the first and most important steps towards finding treatments to stop it. This has been the case for such brain-degenerating conditions as Alzheimer's disease. ...
Parkinson's & Movement disorders
Nov 15, 2012 |
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Dermatitis could be suppressed as it develops
Excessive immune reactions against the body's own skin cells can lead to painful and even chronic dermatitis. An international team of researchers at the MedUni Vienna, the MedUni Graz and the Salk Institute ...
Immunology
Nov 09, 2012 |
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Mouse model exposes a new type of T cell to target melanoma
Cancers arise in the body all the time. Most are nipped in the bud by the immune response, not least by its T cells, which detect telltale molecular markers—or antigens—on cancer cells and destroy them before they grow ...
Cancer
Oct 24, 2012 |
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CAMH protein discovery may lead to new treatment to prevent smoking relapse
Scientists at the Centre for Addiction and Mental Health (CAMH) have identified a potential new approach to preventing smoking relapse, which occurs frequently in smokers who attempt to quit, despite current treatments.
Health
Oct 22, 2012 |
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Helping ex-smokers resist the urge
A new inhibitor helps previously nicotine-addicted rats stay on the wagon, according to a study published on October 22nd in the Journal of Experimental Medicine.
Addiction
Oct 22, 2012 |
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Breakthrough could help sufferers of fatal lung disease
Pioneering research conducted by the University of Sheffield is paving the way for new treatments which could benefit patients suffering from the fatal lung disease pulmonary arterial hypertension (PAH).
Medical research
Oct 15, 2012 |
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Sugar-free approach to treating Kaposi sarcoma
A sugar-loving protein drives the growth of Kaposi sarcoma (KS) tumors, according to a study published on October 1st in The Journal of Experimental Medicine. Interfering with these sugary interactions inhibited growth of Kap ...
Cancer
Oct 01, 2012 |
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Langerhans cells migrate to their final destination in multiple waves at different stages of embryonic development
As our primary interface with the outside world, the skin needs to be able to protect itself against infectious threats. Specialized cells known as Langerhans cells (LCs) (see image) are an essential component ...
Medical research
Aug 29, 2012 |
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Key function of protein discovered for obtaining blood stem cells as source for transplants
Researchers from IMIM (Hospital del Mar Medical Research Institute) have deciphered the function executed by a protein called β-catenin in generating blood tissue stem cells. These cells, also called ...
Medical research
Jul 25, 2012 |
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Helper T cells, not killer T cells, might be responsible for clearing hepatitis A infection
Helper cells traditionally thought to only assist killer white blood cells may be the frontline warriors when battling hepatitis A infection. These are the findings from a Nationwide Children's Hospital study appearing in ...
Diseases, Conditions, Syndromes
Jul 16, 2012 |
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TLR1 protein drives immune response to certain food-borne illness in mice
A naturally occurring protein called TLR1 plays a critical role in protecting the body from illnesses caused by eating undercooked pork or drinking contaminated water, according to new research from the University of Southern ...
Medical research
Jul 10, 2012 |
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Scientists link 'oncometabolite' to onset of acute myeloid leukemia
A team of international scientists led by principal investigator Dr. Tak Mak at the Princess Margaret Cancer Centre, University Health Network, has identified a causative link between the product of a mutated metabolic enzyme ...
Cancer
Jul 04, 2012 |
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Mystery to the origin of long-lived, skin-deep immune cells uncovered
Scientists at A*STAR’s Singapore Immunology Network (SIgN) uncovered the origin of a group of skin-deep immune cells that act as the first line of defence against harmful germs and skin infections. SIgN scientists discovered ...
Immunology
Jun 07, 2012 |
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