Journal of Immunology
Discovery shows fat triggers rheumatoid arthritis
Scientists have discovered that fat cells in the knee secrete a protein linked to arthritis, a finding that paves the way for new gene therapies that could offer relief and mobility to millions worldwide.
Arthritis & Rheumatism
May 08, 2013 |
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Insights obtained by profiling immune response to repeat viral infections could assist vaccine design efforts
Patients who successfully beat infection with dengue virus remain vulnerable to reinfection by other dengue variants, and these secondary infections tend to be more severe. The antibodies arising from the ...
Immunology
Mar 27, 2013 |
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Researchers identify a promising target for multiple sclerosis treatments
A team of basic and clinical scientists led by the University of Montreal Hospital Research Centre's (CRCHUM) Dr. Nathalie Arbour has opened the door to significantly improved treatments for the symptoms of Multiple Sclerosis ...
Immunology
Mar 19, 2013 |
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Protein implicated in lupus promotes disease progression by distinct mechanisms in different immune cells
Patients with systemic lupus erythematosus (SLE) come under attack by their immune system, producing 'autoantibodies' that inflict damage throughout the body. Antibodies normally target foreign proteins, ...
Immunology
Mar 13, 2013 |
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Mechanisms regulating inflammation associated with type 2 diabetes, cancer identified
A study led by researchers at Boston University School of Medicine (BUSM) has identified epigenetic mechanisms that connect a variety of diseases associated with inflammation. Utilizing molecular analyses of gene expression ...
Immunology
Mar 01, 2013 |
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Molecular basis identified for tissue specific immune regulation in the eye and kidney
Scientists at The University of Manchester have made important advances in understanding why our immune system can attack our own tissues resulting in eye and kidney diseases. It is hoped the research will pave the way for ...
Immunology
Feb 20, 2013 |
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Research team explains important step in the activation of T-cells in the immune system
A team, headed by Prof. Dr. Wolfgang Schamel from the Institute of Biology III of the University of Freiburg and Prof. Dr. Balbino Alarcón from the Center for Molecular Biology Severo Ochoa of the Autonomous ...
Immunology
Feb 07, 2013 |
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Immune system can use melanoma's own proteins to kill off cancer cells
Though a small group of proteins, the family called Ras controls a large number of cellular functions, including cell growth, differentiation, and survival. And because the protein has a hand in cellular division, mutated ...
Cancer
Feb 04, 2013 |
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Researchers uncover gene's role in rheumatoid arthritis, findings pave way for new treatments
University of Michigan research sheds new light on why certain people are more likely to suffer from rheumatoid arthritis – paving the way to explore new treatments for both arthritis and other autoimmune diseases.
Arthritis & Rheumatism
Jan 24, 2013 |
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Cerebral malaria: Pinpointing a potential therapeutic target
An excessive response of the immune system to malarial infection can lead to serious complications, such as cerebral malaria. While the mechanism causing the onset of cerebral malaria is unclear, immunologists ...
Immunology
Jan 16, 2013 |
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Identification of developmental 'master switch' helps scientists explore function of infection-preventing cells
Every bite of food or drink of water is an invitation for potentially harmful bacteria and viruses to set up shop in the body. In order to protect against such invaders, the mucous membrane that lines the ...
Immunology
Dec 14, 2012 |
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Researchers shed light on the workings of the body's immune response
Researchers from Queen Mary, University of London have discovered that two proteins which are believed to play a key role in controlling the body's immune response are found in lower levels in T lymphocytes from patients ...
Immunology
Dec 12, 2012 |
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Researchers say effective immunotherapy for melanoma hinges on blocking suppressive factors
(Medical Xpress)—Researchers at the Moffitt Cancer Center have found that delayed tumor growth and enhanced survival of mice bearing melanoma were possible by blocking the reconstitution of myeloid-derived suppressor cells ...
Immunology
Dec 11, 2012 |
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Research suggests a new strategy to prevent or halt periodontal disease
Periodontitis, a form of chronic gum disease that affects nearly half of the U.S. adult population, results when the bacterial community in the mouth becomes unbalanced, leading to inflammation and eventually bone loss. In ...
Medical research
Dec 07, 2012 |
4.8 / 5 (6) |
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Study identifies a potential cause of Parkinson's disease
Deciphering what causes the brain cell degeneration of Parkinson's disease has remained a perplexing challenge for scientists. But a team led by scientists from The Scripps Research Institute (TSRI) has pinpointed ...
Parkinson's & Movement disorders
Nov 19, 2012 |
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