Journal of Immunology

Immunology

Multitasking protein keeps immune system healthy

The polymeric immunoglobulin receptor, or pIgR, is a multitasking protein produced in the lining of mucosal surfaces, such as the intestines. It plays a pivotal role in the body's immune functions by sequestering bacteria ...

Immunology

M-CSF plays role in host defense in bacterial pneumonia

(HealthDay)—The cytokine M-CSF promotes survival of lung and liver mononuclear phagocytes to mediate host defense during bacterial pneumonia, according to an experimental study published in the June 15 issue of The Journal ...

Immunology

Pneumonia discovery may offer way to boost body's defenses

A molecule being targeted in cancer is also critical for the immune system's ability to battle pneumonia, researchers at the University of Virginia School of Medicine have determined. The finding may offer a new way for doctors ...

Oncology & Cancer

OVC cancer breakthrough leads to human clinical trials

Cancer treatment in people could be transformed thanks to a study on treating cancer in animals led by researchers from the Ontario Veterinary College (OVC) at the University of Guelph.

Immunology

Body's early immune response aids cancer growth

Queensland researchers have discovered that the first-stage response of the immune system can contribute to melanoma, colon and breast cancer growth, rather than helping the body to fight it.

Immunology

The therapeutic antibody eculizumab caught in action

In collaboration with Alexion Pharmaceuticals, Inc., scientists from Aarhus University have used X-rays to understand how the therapeutic antibody eculizumab prevents our immune system from destroying red blood cells and ...

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