Journal of Immunology

Immunology

Flu vaccine research: overcoming 'original sin'

(Medical Xpress) -- Scientists studying flu vaccines have identified ways to overcome an obstacle called "original antigenic sin," which can impair immune responses to new flu strains.

Immunology

Asthma's androgen connection

Women are more prone to developing asthma, particularly more severe types of asthma, compared to men. Studies have shown that the sex hormones, estrogen and testosterone, influence the mechanisms driving airway inflammation ...

Immunology

How to make the tuberculosis vaccine more effective

Briefly blocking a key molecule when administering the only approved vaccine for tuberculosis vastly improves long-term protection against the devastating disease in mice, researchers from Texas Biomedical Research Institute ...

Immunology

Researchers makes 'natural born killer' cell discovery

An unexpected role for a white blood cell called the Natural Killer (NK) cell - a critical cell for ridding the body of infection and cancer, has been discovered by researchers at New Zealand's University of Otago.

Immunology

Cytokine may play a major role in multiple sclerosis

Multiple sclerosis (MS) is caused by immune cells that activate a cascade of chemicals in the brain, attacking and degrading the insulation that keeps neuronal signals moving. These chemicals, called cytokines, drive the ...

Immunology

Researchers answer long-standing question about lupus

For years, biomedical researchers have suspected that a specific set of immune cells are responsible for causing disease in lupus patients, but until now they haven't known for sure one way or the other.

Immunology

M-CSF plays role in host defense in bacterial pneumonia

(HealthDay)—The cytokine M-CSF promotes survival of lung and liver mononuclear phagocytes to mediate host defense during bacterial pneumonia, according to an experimental study published in the June 15 issue of The Journal ...

Diseases, Conditions, Syndromes

How herpesviruses shape the immune system

Cytomegalovirus is widespread and remains in the body for a lifetime after infection. In healthy individuals, this virus is usually kept in check, but can become dangerous when the immune system is weakened or during pregnancy. ...

Diseases, Conditions, Syndromes

Partial bone marrow transplant 'rescues' mice with cystic fibrosis

Scientists at La Jolla Institute for Immunology (LJI) have found they can dramatically improve survival of mice with cystic fibrosis through a partial bone marrow transplant. Their new study in the Journal of Immunology shows ...

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