Journal of Medicinal Chemistry

Scientist creates new cancer drug that is ten times more potent

Legend has it that Ralph Waldo Emerson once said, "Build a better mousetrap, and the world will beat a path to your door." University of Missouri researchers are doing just that, but instead of building mousetraps, ...

Cancer created Aug 29, 2012 | popularity 5 / 5 (9) | comments 1 | with audio podcast

Purdue-designed molecule one step closer to possible Alzheimer's treatment

(Medical Xpress)—A new molecule designed to treat Alzheimer's disease has significant promise and is potentially the safest to date, according to researchers.

Medical research created Oct 03, 2012 | popularity not rated yet | comments 1 | with audio podcast

Trojan horse drug therapy provides new approach to treating breast cancer

When Linda Tuttle was diagnosed with breast cancer, she never imagined her experience would inspire her colleagues to design new treatments to tackle the disease.

Cancer created Oct 02, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Novel drug candidates offer new route to controlling inflammation

Pursuing a relatively untapped route for regulating the immune system, an international team of researchers has designed and conducted initial tests on molecules that have the potential to treat diseases involving ...

Inflammatory disorders created May 14, 2012 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Novel anti-malarial drug target identified

An international team of scientists, led by researchers from the Department of Pediatrics at the University of California, San Diego School of Medicine, have identified the first reported inhibitors of a key ...

Medical research created Jul 19, 2012 | popularity 4 / 5 (2) | comments 0 | with audio podcast

Novel designed molecules could stop colon cancer metastasis

A Basque research consortium has managed to stop the development of colon cancer and its liver metastasis in an experimental model using mice. This breakthrough, which could open new avenues for the future treatment of these ...

Cancer created Feb 14, 2013 | popularity 2 / 5 (1) | comments 1

Marine compound discovery shows promise of improved drug treatment for COPD patients

(Medical Xpress)—Pharmacy researchers at the University of Florida have isolated a new marine compound they believe may lead to improved drug therapies for pulmonary diseases by inhibiting their progression rather than ...

Diseases, Conditions, Syndromes created Feb 28, 2013 | popularity not rated yet | comments 0

New malaria drug requires just one dose and appears twice as effective as existing regimen

Scientists are reporting development of a new malaria drug that, in laboratory tests, has been twice as effective as the best current medicine against this global scourge and may fight off the disease with ...

Diseases, Conditions, Syndromes created Oct 17, 2012 | popularity not rated yet | comments 0

A non-antibiotic approach for treating urinary tract infections

A potential new approach for treating urinary tract infections (UTIs) — which affect millions of people annually — without traditional antibiotics is being reported in ACS' Journal of Medicinal Ch ...

Medical research created Jun 20, 2012 | popularity 5 / 5 (1) | comments 0

Discovering new uses for old drugs

With the cost of putting a single new drug on the pharmacy shelves topping a staggering $1 billion, scientists are reporting development of a way to determine if an already-approved drug might be used to treat ...

Medications created Aug 01, 2012 | popularity not rated yet | comments 0

Researchers develop novel treatment for prostate cancer

(Medical Xpress)—The work of a team of Wake Forest researchers developing a novel drug for prostate cancer treatment is featured on the cover of the Nov. 26 issue of the Journal of Medicinal Chemistry.

Cancer created Nov 29, 2012 | popularity 5 / 5 (2) | comments 0

Researchers studying defective protein in search of cystic fibrosis treatment

(Medical Xpress) -- Cystic fibrosis is the most common fatal genetic disease affecting Canadian children and young adults, more than two children each and every week are diagnosed with cystic fibrosis (CF). ...

Diseases, Conditions, Syndromes created Mar 28, 2012 | popularity not rated yet | comments 0

Researchers design new substances that might help fight Alzheimer's and Parkinson's disease

University of Granada researchers have tested melatonin analogues in rats that inhibit the enzyme nitric oxide synthase, which is involved in the development of the diseases referred above.

Medical research created Jun 13, 2012 | popularity not rated yet | comments 0