Journal of the American Society of Nephrology

Diseases, Conditions, Syndromes

New window on fibrosis

DDR1 is a receptor tyrosine kinase (RTK)—a cell surface receptor—that regulates multiple functions including the maintenance of the normal structure of tissues, but which also contributes to pathological conditions including ...

Diseases, Conditions, Syndromes

Sex differences in kidney injury

Evidence indicates men have higher incidence of chronic kidney disease and quicker renal decline than premenopausal women. However, sex differences in the expression and activation of the EGF receptor (EGFR), which mediates ...

Diseases, Conditions, Syndromes

Higher eGFR at dialysis initiation tied to lower survival in children

(HealthDay)—In children with end-stage renal disease (ESRD), a higher estimated glomerular filtration rate (eGFR) at dialysis initiation is associated with lower survival, particularly among children whose initial treatment ...

Diseases, Conditions, Syndromes

Study reveals new genetic factors linked to kidney stones

Researchers have discovered new genetic factors that likely contribute to the development of kidney stones. The findings, which appear in an upcoming issue of the Journal of the American Society of Nephrology (JASN), may ...

Diseases, Conditions, Syndromes

NUP160 genetic mutation linked to steroid-resistant nephrotic syndrome

Mutations in the NUP160 gene, which encodes one protein component of the nuclear pore complex nucleoporin 160 kD, are implicated in steroid-resistant nephrotic syndrome, an international team reports March 25, 2019, in JASN. ...

Diseases, Conditions, Syndromes

New approach performs well for measuring CKD quality of life

(HealthDay)—A new chronic kidney disease (CKD) measure of quality of life (QOL) and a single-score summary for the Kidney Disease Quality of Life-36 (KDQOL-36) are both reliable for assessing patient-reported outcomes and ...

Diseases, Conditions, Syndromes

Study provides new insights on common post-transplant condition

New research may help clinicians determine which patients with a condition that commonly arises after kidney transplantation are at high risk of transplant failure. The findings appear in an upcoming issue of the Journal ...

page 9 from 37