Molecular and Cellular Biology

Molecular biology ( /məˈlɛkjʊlər/) is the branch of biology that deals with the molecular basis of biological activity. This field overlaps with other areas of biology and chemistry, particularly genetics and biochemistry. Molecular biology chiefly concerns itself with understanding the interactions between the various systems of a cell, including the interactions between the different types of DNA, RNA and protein biosynthesis as well as learning how these interactions are regulated. Writing in Nature in 1961, William Astbury described molecular biology as Researchers in molecular biology use specific techniques native to molecular biology but increasingly combine these with techniques and ideas from genetics and biochemistry. There is not a defined line between these disciplines. The figure above is a schematic that depicts one possible view of the relationship between the fields: Much of the work in molecular biology is quantitative, and recently much work has been done at the interface of molecular biology and computer science in bioinformatics and computational biology. As of the early 2000s, the study of gene structure and function, molecular genetics, has been among the most

Publisher
American Society for Microbiology
Country
United States
History
1981–present
Impact factor
5.942 (2008)
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Single enzyme is necessary for development of diabetes

An enzyme called 12-LO promotes the obesity-induced oxidative stress in the pancreatic cells that leads to pre-diabetes, and diabetes. 12-LO's enzymatic action is the last step in the production of certain small molecules ...

Aug 14, 2014
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Shape-shifting stops migrating cancer cells

Like a car with a front and back end, a steering mechanism and an engine to push it forward, cancer cells propel themselves through normal tissues and organs to spread cancer throughout the body. Researchers at Mayo Clinic ...

Dec 04, 2013
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Protein predicts breast cancer prognosis

Researchers have identified a protein that they believe may help predict breast cancer prognosis, potentially relieving thousands of women at low risk from having to undergo painful, oft-debilitating therapies, while insuring ...

Aug 29, 2013
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Hydrogen sulfide: The next anti-aging agent?

Hydrogen sulfide (H2S) may play a wide-ranging role in staving off aging, according to a paper published online ahead of print in the journal Molecular and Cellular Biology. In this review article, a team from China explor ...

Jan 29, 2013
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New technique catalogs lymphoma-linked genetic variations

(Medical Xpress)—As anyone familiar with the X-Men knows, mutants can be either very good or very bad—or somewhere in between. The same appears true within cancer cells, which may harbor hundreds of mutations that set ...

Dec 27, 2012
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