Molecular Cell
Methylome modifications offer new measure of our 'biological' age
Women live longer than men. Individuals can appear or feel years younger – or older – than their chronological age. Diseases can affect our aging process. When it comes to biology, our clocks clearly tick differently.
Medical research
Nov 21, 2012 |
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New developments reveal a molecule with a promising function in terms of cancer treatment.
Researchers from Inserm and CNRS from the Institute for genetics and molecular and cellular biology (IGBMC) and from the Research Institute at the Strasbourg school of biotechnology (Irebs) have focussed their efforts on ...
Cancer
Oct 30, 2012 |
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Discovery of new type of RNA could have implications for some congenital disorders
State funding of stem cell research at the UConn Health Center has led one research team to the discovery of a new type of RNA that could one day result in the successful treatment of devastating congenital disorders such ...
Medical research
Oct 29, 2012 |
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Target for obesity drugs comes into focus
(Medical Xpress)—Researchers at the University of Michigan have determined how the hormone leptin, an important regulator of metabolism and body weight, interacts with a key receptor in the brain.
Medical research
Oct 11, 2012 |
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Cell death discovery suggests new ways to protect female fertility
Melbourne researchers have identified a new way of protecting female fertility, offering hope to women whose fertility may be compromised by the side-effects of cancer therapy or by premature menopause.
Medical research
Sep 22, 2012 |
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Uncovering the genome's regulatory code
Since the sequencing of the human genome in 2001, all our genes – around 20,000 in total – have been identified. But much is still unknown – for instance where and when each is active. Next to each ...
Genetics
Sep 10, 2012 |
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Binding sites for LIN28 protein found in thousands of human genes
A study led by researchers at the UC San Diego Stem Cell Research program and funded by the California Institute for Regenerative Medicine (CIRM) looks at an important RNA binding protein called LIN28, which ...
Genetics
Sep 04, 2012 |
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New regulatory mechanism discovered in cell system for eliminating unneeded proteins
A faulty gene linked to a rare blood vessel disorder has led investigators to discover a mechanism involved in determining the fate of possibly thousands of proteins working inside cells.
Medical research
Aug 10, 2012 |
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Inflammatory pathway spurs cancer stem cells to resist HER2-targeted breast cancer treatment
Breast cancer treatments such as Herceptin that target a marker called HER2 have dramatically improved outcomes for women with this type of cancer. But nearly half of these cancers are resistant to Herceptin from the start ...
Cancer
Jul 19, 2012 |
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Does presence of oxidants early in life help determine life span?
Why do we age, and what makes some of us live longer than others? For decades, researchers have been trying to answer these questions by elucidating the molecular causes of aging.
Medical research
Jul 19, 2012 |
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Enzyme offers new therapeutic target for cancer drugs
Researchers at the University of California, San Diego School of Medicine have uncovered a new signal transduction pathway specifically devoted to the regulation of alternative RNA splicing, a process that allows a single ...
Cancer
Jun 21, 2012 |
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Researchers reveal crucial immune fighter role of the STING protein
Researchers at Weill Cornell Medical College have unlocked the structure of a key protein that, when sensing certain viruses and bacteria, triggers the body's immediate immune response.
Medical research
Jun 18, 2012 |
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Key gene found responsible for chronic inflammation, accelerated aging and cancer
Researchers at NYU School of Medicine have, for the first time, identified a single gene that simultaneously controls inflammation, accelerated aging and cancer.
Genetics
May 24, 2012 |
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Scientists study serious immune malfunction
Defects in the gene that encodes the XIAP protein result in a serious immune malfunction. Scientists used biochemical analyses to map the protein's ability to activate vital components of the immune system. Their results ...
Immunology
May 17, 2012 |
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A small cut with a big impact
Diseases and injuries trigger warning signals in our cells. As a result, genes are expressed and proteins produced, modified or degraded to adapt to the external danger and to protect the organism. In order to be able to ...
Genetics
May 02, 2012 |
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