Molecular Cell

Genetics

An unprecedented view of gene regulation

Much of the human genome is made of regulatory regions that control which genes are expressed at a given time within a cell. Those regulatory elements can be located near a target gene or up to 2 million base pairs away from ...

Oncology & Cancer

Researchers identify key source of T cell 'exhaustion'

Custom-made to attack cancer cells, CAR T-cell therapies have opened a new era in the treatment of human cancers, particularly, in hematologic malignancies. All too often, however, they display a frustrating trait inherited ...

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