Molecular Cell
Research identifies a way to make cancer cells more responsive to chemotherapy
Breast cancer characterized as "triple negative" carries a poor prognosis, with limited treatment options. In some cases, chemotherapy doesn't kill the cancer cells the way it's supposed to. New research from Western University ...
Cancer
May 23, 2013 |
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Protein preps cells to survive stress of cancer growth and chemotherapy
Scientists have uncovered a survival mechanism that occurs in breast cells that have just turned premalignant-cells on the cusp between normalcy and cancers-which may lead to new methods of stopping tumors.
Cancer
May 23, 2013 |
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Faulty energy production in brain cells leads to disorders ranging from Parkinson's to intellectual disability
Neuroscientist Patrik Verstreken of VIB (Flanders Institute for Biotechnology) and KU Leuven has shown for the first time that dysfunctional mitochondria in brain cells can lead to learning disabilities. The link between ...
Parkinson's & Movement disorders
May 17, 2013 |
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Inhibiting enzymes in the cell may lead to development and proliferation of cancer cells
Blocking certain enzymes in the cell may prevent cancer cell division and growth, according to new findings from researchers at the Graduate School of Biomedical Sciences at the Icahn School of Medicine at Mount Sinai. The ...
Cancer
Apr 25, 2013 |
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DNA sequencing: Changing the landscape of science and biology
UConn researchers are at the forefront of new discoveries and understanding about the smallest molecules in the body that can have a momentous impact on human health.
Genetics
Mar 26, 2013 |
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Cancer-promoting protein found to also suppress cell growth
Some cellular proteins have multiple, and occasionally opposing, functions. Professor Adrian Krainer [link: Faculty profile] and colleagues at Cold Spring Harbor Laboratory demonstrate in a paper published online today in ...
Medical research
Mar 07, 2013 |
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Why cells stick: Phenomenon extends longevity of bonds between cells
Research carried out by scientists at the Georgia Institute of Technology and The University of Manchester has revealed new insights into how cells stick to each other and to other bodily structures, an essential function ...
Medical research
Feb 14, 2013 |
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Scientists link excess sugar to cancer
Sugars are needed to provide us with energy and in moderate amounts contribute to our well-being. Sustained high levels of sugars, as is found in diabetics, damages our cells and now is shown that can also ...
Medical research
Feb 01, 2013 |
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Team uncovers new insight into cell development and cancer
Long-standing research efforts have been focused on understanding how stem cells, cells capable of transforming into any type of cell in the body, are capable of being programmed down a defined path to contribute ...
Cancer
Dec 27, 2012 |
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Protein kinase Akt identified as arbiter of cancer stem cell fate, paper reports
(Medical Xpress)—The protein kinase Akt is a key regulator of cell growth, proliferation, metabolism, survival, and death. New work on Akt's role in cancer stem cell biology from the lab of senior author ...
Cancer
Dec 20, 2012 |
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Insight into DNA reprogramming during egg and sperm cell development
Scientists at the Babraham Institute have gained a new understanding of when and how the DNA in developing egg and sperm cells is 'reset', in preparation for making a new embryo. It is well known that small chemical groups ...
Genetics
Dec 06, 2012 |
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Researchers ID gene that turns carbs into fat: Discovery could help development of treatment for fatty liver, diabetes
A gene that helps the body convert that big plate of holiday cookies you just polished off into fat could provide a new target for potential treatments for fatty liver disease, diabetes and obesity.
Genetics
Dec 06, 2012 |
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Scientists create roadmap to metabolic reprogramming for aging
In efforts to understand what influences life span, cancer and aging, scientists are building roadmaps to navigate and learn about cells at the molecular level.
Medical research
Nov 29, 2012 |
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Metabolic protein launches sugar feast that nurtures brain tumors
Researchers at The University of Texas MD Anderson Cancer Center have tracked down a cancer-promoting protein's pathway into the cell nucleus and discovered how, once there, it fires up a glucose metabolism pathway on which ...
Cancer
Nov 26, 2012 |
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Genome packaging: Key to breast cancer development
Cancer is a complex disease and only thanks to advances in genomic techniques have researchers begun to understand, at a cellular and molecular level, the mechanisms which are disrupted in cancer cells. This ...
Cancer
Nov 22, 2012 |
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