Molecular Cell

Medical research

Scientists identify new human genes controlling HIV infection

Viruses are parasites. The only way they can grow is by hijacking their hosts. When they infect a human host, viruses use human proteins to multiply and modify the human cells to sustain the infection. At the same time, the ...

Medical research

Fat droplets play surprise role in metabolism

In suspense novels, the most unassuming character sometimes turns out to be a mastermind, influencing events without attracting attention. That same storyline may be afoot in cells as well: an unglamorous fat-storing droplet ...

Psychology & Psychiatry

Scientists discover link between autism and cognitive impairment

Autism can bestow brilliance as well as cognitive difficulty, but how either scenario plays out in the brain is not clear. Now a study by University of Toronto researchers has found that a tiny gene fragment impacts the brain ...

Medical research

Cancer cells can reuse apparent 'dead end metabolites'

Researchers at Winship Cancer Institute of Emory University have discovered that an apparent "dead end metabolite" has a previously unknown function regulating cell growth. The finding could guide efforts to target cancer ...

Genetics

How your DNA takes shape makes a big difference in your health

The more we learn about our genome, the more mysteries arise. For example, how can people with the same disease-causing mutation have different disease progression and symptoms? And despite the fact that it's been more than ...

Medical research

Novel paradigm in drug development

Traditional medicines mostly function as inhibitors, attacking the disease-relevant proteins that cause cancer, by binding to their accessible pockets. Following this strategy, only ~20% of all proteins are chemically addressable, ...

page 9 from 19