Molecular Therapy

Oncology & Cancer

Research points to potential new treatment for pancreatic cancer

As the next step in finding a potential targeted treatment for pancreatic cancer, researchers at the University of Cincinnati are publishing a new study revealing how a combination therapy may improve outcomes for patients ...

HIV & AIDS

Nowhere to hide: Treatment targets HIV's last hiding place

While HIV is no longer the death sentence it once was, we are yet to defeat it entirely. However, a new study from Oxford University offers hope that HIV will eventually have nowhere to hide. Tom Calver spoke to Professor ...

Medical research

Fat cell hormone boosts potential of stem cell therapy

Mesenchymal stem cells (MSCs) have the potential to differentiate into a range of different cell types, including bone, fat and muscle cells. But it's their ability to stimulate the repair of damaged tissue that has captured ...

Diseases, Conditions, Syndromes

Synthetic antibody rapidly protects mice and monkeys from Zika

A DNA-encoded monoclonal antibody prevents Zika infection in mice and non-human primates, researchers report April 5th in the journal Molecular Therapy. Injections of synthetic DNA encoding the potent anti-Zika monoclonal ...

HIV & AIDS

Stem cell gene therapy holds promise for eliminating HIV infection

cientists at the UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research are one step closer to engineering a tool that could one day arm the body's immune system to fight HIV—and win. The new technique ...

Neuroscience

Gene immunotherapy protects against multiple sclerosis in mice

A potent and long-lasting gene immunotherapy approach prevents and reverses symptoms of multiple sclerosis in mice, according to a study published September 21st in the journal Molecular Therapy. Multiple sclerosis is an ...

Genetics

Genetic editing shows promise in Duchenne muscular dystrophy

Using a novel genetic 'editing' technique, Duke University biomedical engineers have been able to repair a defect responsible for one of the most common inherited disorders, Duchenne muscular dystrophy, in cell samples from ...

Medical research

Gene therapy cassettes improved for muscular dystrophy

Experimental gene therapy cassettes for Duchenne muscular dystrophy have been modified to deliver better performance. The cassettes, which carry the therapy into muscle cells, contain newer versions of a miniaturized treatment ...

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