Nature Immunology

Survival gene may be key to controlling HIV and hepatitis

(Medical Xpress)—A newly discovered gene that is essential for embryo survival could also hold the key to treating and potentially controlling chronic infections such as HIV, hepatitis and tuberculosis.

Immunology created Nov 26, 2012 | popularity 5 / 5 (3) | comments 0 | with audio podcast

The HOIL1 gene: The cause of a new rare disease

The researcher Capucine Picard, working with the team from Inserm unit 980 "Human genetics and infections diseases"/Université Paris Descartes under the leadership of Jean-Laurent Casanova, along with researchers from a ...

Immunology created Nov 01, 2012 | popularity not rated yet | comments 0

Insights into rare immune cells that keep blood stem cells in a youthful state may lead to better treatments

Hiding deep inside the bone marrow are special cells. They wait patiently for the hour of need, at which point these blood forming stem cells can proliferate and differentiate into billions of mature blood ...

Immunology created Oct 22, 2012 | popularity not rated yet | comments 0 | with audio podcast

Key mechanism for controlling body's inflammatory response discovered

Researchers at Queen Mary, University of London have discovered how a key molecule controls the body's inflammatory responses. The molecule, known as p110delta, fine-tunes inflammation to avoid excessive reactions that can ...

Immunology created Sep 30, 2012 | popularity 5 / 5 (6) | comments 0 | with audio podcast

Solving puzzle of B-cell lymphoma development

Germinal centers are sites in the organs of the lymphatic system, formed during the course of an immune response to infection, where B cells intensely proliferate and modify their DNA in order to produce ...

Immunology created Sep 23, 2012 | popularity 4.9 / 5 (7) | comments 0 | with audio podcast

Identifying the key genes to infection resistance

Manning the gates of our immune system are toll-like receptors (TLR)—tiny hairs that stick out of the cell membrane, recognize foreign bodies, and rally an organism's defense mechanisms. The molecular building ...

Immunology created Sep 17, 2012 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Lipids produced within the thymus give immune cells the initial boost they need to fight off infection

Semi-invariant natural killer T (iNKT) cells wage war against infectious threats, attacking microbial cells and generating signals that enable other immune cells also to respond aggressively. iNKT cells initially ...

Immunology created Sep 12, 2012 | popularity not rated yet | comments 0

Scientists find missing link between stem cells, immune system

UCLA researchers have discovered a type of cell that is the "missing link" between bone marrow stem cells and all the cells of the human immune system, a finding that will lead to a greater understanding of how a healthy ...

Immunology created Sep 02, 2012 | popularity 3.9 / 5 (8) | comments 0 | with audio podcast

Immunological genome project researchers probe every type of immune cell

(Medical Xpress)—They haven't cured the common cold yet, but a nationwide "big science" team aims to identify new strategies for orchestrating immune responses to better fight disease.

Immunology created Aug 30, 2012 | popularity not rated yet | comments 0 | with audio podcast

Manipulating the microbiome could help manage weight

Vaccines and antibiotics may someday join caloric restriction or bariatric surgery as a way to regulate weight gain, according to a new study focused on the interactions between diet, the bacteria that live in the bowel, ...

Immunology created Aug 26, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Immune system uses heart channel to select powerful defenders

(Medical Xpress) -- When the body makes immune T cells, it relies on a molecular channel more commonly seen in nerves and heart muscles to ensure that the powerful T cells have the right mixture of aggressiveness ...

Immunology created Aug 16, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Key signal prepares immune cells to defend skin, brain

(Medical Xpress) -- Scientists at Washington University School of Medicine in St. Louis have identified the molecular signal that triggers the development of immune cells that patrol the skin and brain.

Immunology created Aug 10, 2012 | popularity 4.5 / 5 (2) | comments 0 | with audio podcast

UNC team describes novel inflammatory protein function

A UNC-led team of scientists describes the function of a previously uncharacterized protein that dramatically influences inflammation.

Immunology created Aug 06, 2012 | popularity not rated yet | comments 0 | with audio podcast

Unsung heroes of antibody production

B cells are the body’s antibody factories, standing by to churn out molecules that selectively target foreign threats as a component of the humoral immune response. However, this process also requires ...

Immunology created Aug 03, 2012 | popularity not rated yet | comments 0

Cell receptor has proclivity for T helper 9 cells, airway inflammation

A research team led by Xian Chang Li, MD, PhD, Brigham and Women's Hospital (BWH) Transplantation Research Center, has shed light on how a population of lymphocytes, called CD4+ T cells, mature into various subsets of adult ...

Immunology created Jul 29, 2012 | popularity not rated yet | comments 0 | with audio podcast