Nature Immunology

Immunology

How autoimmune disease is prevented—mechanism discovered

A previously unknown safety mechanism in our immune system keeps the body free from autoimmune diseases. Researchers from Karolinska Institutet have discovered that a cell in our inherited immune system can prevent our adaptive ...

Diseases, Conditions, Syndromes

The role of T-cells in SARS-CoV-2 virus defense

Our immune system can efficiently fend off viral diseases. T-cells can directly destroy virus-infected cells and enable the formation of efficient, virus-neutralizing antibodies by B-cells. These two cell types also play ...

Immunology

How immune cells activate the killer mode

Unraveling a key motif: The T lymphocytes of the immune system work to destroy infected cells or cancer cells. To do so, they have to identify the threat: Molecules perceived as foreign—so-called antigens—bind to the ...

HIV & AIDS

Diabetes drug may be a new weapon against HIV

A team led by scientists at the UNC School of Medicine discovered an important vulnerability of the AIDS-causing retrovirus HIV, and has shown in preclinical experiments that a widely used diabetes drug, metformin, seems ...

Immunology

Cancer cells hijack glucose, alter immune cells

When cancer cells compete with immune cells for glucose, the cancer wins. As a result, the immune T cells are not healthy and don't have the weapons to kill the cancer.

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