Nature Structural & Molecular Biology

Telomere shortening affects muscular dystrophy gene

(Medical Xpress)—Facioscapulohumeral muscular dystrophy (FSHD) is a genetic disorder that causes the muscles of the upper body to waste away. It is unusual in that symptoms do not usually appear until sufferers are in their ...

Genetics created May 06, 2013 | popularity 4.8 / 5 (4) | comments 3 | with audio podcast report

Mapping of cancer cell fuel pumps paves the way for new drugs

For the first time, researchers at Karolinska Institutet in Sweden have managed to obtain detailed images of the way in which the transport protein GLUT transports sugars into cells. Since tumours are highly dependent on ...

Cancer created Apr 28, 2013 | popularity 4.7 / 5 (3) | comments 0 | with audio podcast

Researchers discover how some natural antibodies are able to stop flu

(Medical Xpress)—Researchers with the Scripps Institute have discovered that three naturally occurring antibodies are able to overcome flu mutations by attaching to a non-changing protein in the flu virus. ...

Medical research created Feb 11, 2013 | popularity 5 / 5 (3) | comments 0 | with audio podcast report

Cracking the epigenetic code, advancing our understanding of disease

(Medical Xpress)—A team of researchers at The Australian National University is one step closer to better understanding how organisms function after discovering how epigenetic information is transmitted ...

Genetics created Oct 22, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Researchers and colleagues identify PHF20, a regulator of gene P53

Researchers at Moffitt Cancer Center and colleagues have identified PHF20, a novel transcriptional factor, and clarified its role in maintaining the stability and transcription of p53, a gene that allows for both normal cell ...

Cancer created Aug 24, 2012 | popularity not rated yet | comments 0 | with audio podcast

Steroid hormone receptor prefers working alone to shut off immune system genes

Researchers at Emory University School of Medicine have obtained a detailed molecular picture that shows how glucocorticoid hormones shut off key immune system genes.

Medical research created Dec 09, 2012 | popularity not rated yet | comments 0 | with audio podcast

Study illuminates roles of novel epigenetic chemical in the brain

Researchers from the Centre for Addiction and Mental Health (CAMH) have identified a new role of a chemical involved in controlling the genes underlying memory and learning.

Genetics created Sep 17, 2012 | popularity 5 / 5 (1) | comments 2 | with audio podcast

Hot on the trail of metabolic diseases and resistance to antibiotics

Proteins belonging to the large and important family of ABC transporters have been associated with metabolic diseases and can cause resistance to antibiotics. Biochemists from the University of Zurich and the NCCR Structural ...

Medical research created Mar 28, 2012 | popularity not rated yet | comments 0

An unexpected player in a cancer defense system

Researchers of the Swedish medical university Karolinska Institutet and the University of Cologne, Germany, have identified a new protein involved in a defense mechanism against cancer. The VCP/p97 complex is best known for ...

Cancer created Nov 28, 2011 | popularity 5 / 5 (1) | comments 0