PLoS Biology

Neuroscience

In Krabbe disease, neurons may bring about their own destruction

The gene defect underlying Krabbe disease causes degeneration of neurons directly, independent of its effects on other cell types, according to a new study publishing July 5 in the open-access journal PLOS Biology by Daesung ...

Medical research

Developmentally arrested IVF embryos can be coaxed to divide

Why do two-thirds of in vitro fertilization (IVF) embryos go into developmental arrest? A new study publishing June 30th in the open-access journal PLOS Biology by Andrew Hutchins of Southern University of Science and Technology ...

Medical research

A new hope for a therapy against retinitis pigmentosa

Retinitis pigmentosa, a degenerative genetic disease of the eye, is characterized by progressive vision loss, usually leading to blindness. In some patients, structural defects in the photoreceptor cells have been observed, ...

Medications

New antibiotics could tackle drug-resistant tuberculosis bacteria

Infection by Mycobacterium tuberculosis kills 1.5 million people worldwide every year. Antibiotics to treat TB exist, but in recent years, multi-drug resistant (MDR), extensively drug-resistant (XDR) and totally drug-resistant ...

Diseases, Conditions, Syndromes

Potential strategy to reduce fatigue after COVID-19 vaccination

Despite their strong effectiveness against SARS-CoV-2, mRNA-based COVID-19 vaccines are associated with adverse post-vaccination effects, such as fatigue; how can this be avoided? In a new study publishing May 31st in the ...

Medical research

Frozen testicular tissue still viable after two decades

Male testis tissue that is cryopreserved can be reimplanted after more than 20 years and will go on to make viable sperm, according to a new study in rodents in the open-access journal PLOS Biology by Eoin Whelan of the School ...

Medical research

Scientists closer to outsmarting malaria parasites

Researchers from The Australian National University (ANU) have discovered why malaria parasites are vulnerable to some drug therapies but resistant to others, offering scientists another piece of the puzzle in the global ...

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