PLoS Biology

Medical research

Anti-amyloid drugs and Alzheimer's disease

An estimated 50 million people around the world have Alzheimer's disease (AD), and perhaps twice that number are unknowingly "incubating" the disease during its long presymptomatic period. The total cost of caring for AD ...

Neuroscience

Sentences have their own timing in the brain

The brain links incoming speech sounds to knowledge of grammar, which is abstract in nature. But how does the brain encode abstract sentence structure? In a neuroimaging study published in PLOS Biology, researchers from the ...

Neuroscience

In Krabbe disease, neurons may bring about their own destruction

The gene defect underlying Krabbe disease causes degeneration of neurons directly, independent of its effects on other cell types, according to a new study publishing July 5 in the open-access journal PLOS Biology by Daesung ...

Medical research

Developmentally arrested IVF embryos can be coaxed to divide

Why do two-thirds of in vitro fertilization (IVF) embryos go into developmental arrest? A new study publishing June 30th in the open-access journal PLOS Biology by Andrew Hutchins of Southern University of Science and Technology ...

Medical research

A new hope for a therapy against retinitis pigmentosa

Retinitis pigmentosa, a degenerative genetic disease of the eye, is characterized by progressive vision loss, usually leading to blindness. In some patients, structural defects in the photoreceptor cells have been observed, ...

Medications

New antibiotics could tackle drug-resistant tuberculosis bacteria

Infection by Mycobacterium tuberculosis kills 1.5 million people worldwide every year. Antibiotics to treat TB exist, but in recent years, multi-drug resistant (MDR), extensively drug-resistant (XDR) and totally drug-resistant ...

Diseases, Conditions, Syndromes

Potential strategy to reduce fatigue after COVID-19 vaccination

Despite their strong effectiveness against SARS-CoV-2, mRNA-based COVID-19 vaccines are associated with adverse post-vaccination effects, such as fatigue; how can this be avoided? In a new study publishing May 31st in the ...

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